Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RARA | P10276 | 1/20 | 0.43 |
| ▸ | RARB | P10826 | 1/20 | 0.43 |
| ▸ | RARG | P13631 | 1/20 | 0.43 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.42 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 3/20 | 0.41 |
| ▸ | RXRB | P28702 | 3/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | BCL2 | P10415 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.41 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.41 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL17005577 | 0.93 | EGFR (0.46) | KMOEGFRALDH1A1MAPK1RARA | |
| Terephthalic Acid SCHEMBL367597 | 0.93 | EGFR (0.49) | KMOEGFRALDH1A1MAPK1RARA | |
| Terephthalic Acid SCHEMBL1234263 | 0.87 | TSHR (0.46) | EGFRALDH1A1MAPK1RXRARXRB | |
| Terephthalic Acid SCHEMBL27428746 | 0.87 | EGFR (0.44) | KMOEGFRRARARARBRARG | |
| Terephthalic Acid SCHEMBL11133121 | 0.87 | RARB (0.48) | EGFRALDH1A1MAPK1RARARARB | |
| SCHEMBL8485036 | 0.86 | BCL2L1 (0.47) | EGFRALDH1A1MAPK1TRIM24TRIM33 | |
| SCHEMBL209608 | 0.85 | CA1 (0.37) | KMOALDH1A1NPC1 | |
| Terephthalic Acid SCHEMBL8151569 | 0.85 | RARB (0.44) | KMOALDH1A1RARARARBRARG | |
| Isophthalic Acid SCHEMBL472832 | 0.84 | KMO (0.47) | KMOALDH1A1KEAP1RXRARXRB | |
| Terephthalic Acid SCHEMBL28622230 | 0.84 | TSHR (0.46) | EGFRRXRARXRBTP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 159 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3608366-B1 | THERMOPLASTIC POLYESTER RESIN COMPOSITION AND MOLDED ARTICLE | TORAY INDUSTRIES (JP) | 2024-03-06 | — | — | EP | claimed |
| US-11319436-B2 | Thermoplastic polyester resin composition and molded article | TORAY INDUSTRIES, INC. (JP) | 2022-05-03 | — | — | US | claimed |
| CN-112739772-A | Thermoplastic polyester resin composition and molded article | 东丽株式会社 | 2021-04-30 | — | — | CN | claimed |
| US-20200172726-A1 | THERMOPLASTIC POLYESTER RESIN COMPOSITION AND MOLDED ARTICLE | TORAY INDUSTRIES, INC. (JP) | 2020-06-04 | — | — | US | claimed |
| EP-3369775-B1 | THERMOPLASTIC POLYESTER RESIN COMPOSITION AND MOLDED ARTICLE | TORAY INDUSTRIES (JP) | 2020-05-06 | — | — | EP | claimed |
| EP-1580766-B1 | INSULATED WIRE AND RESIN DISPERSION | FURUKAWA ELECTRIC CO LTD (JP) | 2014-12-31 | — | — | EP | claimed |
| WO-2024135597-A1 | METHOD FOR PRODUCING POLYESTER RESIN, AND POLYESTER RESIN | 東レ株式会社 | 2024-06-27 | — | — | WO | disclosed |
| CN-118234803-A | Thermoplastic polyester resin composition and molded article | 东丽株式会社 | 2024-06-21 | — | — | CN | disclosed |
| EP-4382562-A1 | INORGANIC FILLING MATERIAL AND INORGANIC FILLING MATERIAL-REINFORCED THERMOPLASTIC RESIN | Toray Industries, Inc. (JP) | 2024-06-12 | — | — | EP | disclosed |
| EP-3835340-B1 | MULTIAXIAL TEXTILE RESIN BASE MATERIAL AND METHOD FOR PRODUCTION THEREOF | TORAY INDUSTRIES (JP) | 2024-05-01 | — | — | EP | disclosed |
| EP-3970942-B1 | COMPOSITE MOLDED ARTICLE | TORAY INDUSTRIES (JP) | 2024-03-27 | — | — | EP | disclosed |
| CN-114206978-B | Thermoplastic polyester resin, thermoplastic polyester resin composition, and molded article | 东丽株式会社 | 2024-03-12 | — | — | CN | disclosed |
| EP-3608366-B1 | THERMOPLASTIC POLYESTER RESIN COMPOSITION AND MOLDED ARTICLE | TORAY INDUSTRIES (JP) | 2024-03-06 | — | — | EP | disclosed |
| US-5852108-A | Composite particulate material for resin reinforcement, production thereof, and reinforced resin composition incorporated therewith | TORAY INDUSTRIES, INC. (JP) | 1998-12-22 | — | — | US | disclosed |
| US-5712334-A | Lacton-modified polyvinyl alcohol and permanently anti-static resin composition | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-01-27 | — | — | US | disclosed |
| EP-0548361-B1 | POLYESTER-GRAFTED POLYAMIDE, PRODUCTION THEREOF, AND THERMOPLASTIC RESIN COMPOSITION PRODUCED THEREFROM | DAICEL CHEM (JP) | 1997-10-29 | — | — | EP | disclosed |
| EP-0742252-A2 | Composite particulate material, production thereof, and reinforced resin composition incorporated therewith | TORAY INDUSTRIES, INC. (JP) | 1996-11-13 | — | — | EP | disclosed |
| EP-0704470-A2 | A lactone-modified polyvinyl alcohol, a process for the preparation thereof, a resin compsition, permanently anti-electrostatic resin composition, a lactone-modified resin having hydroxyl groups, and a process for the preparation thereof | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1996-04-03 | — | — | EP | disclosed |
| US-5317066-A | Hydroxylated polyamides reacting with a polyester; compatibilizers for polyamide/ester molding blends; workability | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1994-05-31 | — | — | US | disclosed |
| EP-0548361-A1 | POLYESTER-GRAFTED POLYAMIDE, PRODUCTION THEREOF, AND THERMOPLASTIC RESIN COMPOSITION PRODUCED THEREFROM | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1993-06-30 | — | — | EP | disclosed |