Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | KMO | O15229 | 1/20 | 0.48 |
| ▸ | RARA | P10276 | 1/20 | 0.45 |
| ▸ | RARB | P10826 | 1/20 | 0.45 |
| ▸ | RARG | P13631 | 1/20 | 0.45 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.45 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 3/20 | 0.44 |
| ▸ | RXRB | P28702 | 3/20 | 0.44 |
| ▸ | RXRG | P48443 | 1/20 | 0.44 |
| ▸ | BCL2 | P10415 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL17005577 | 0.96 | EGFR (0.46) | EGFRKMORARARARBRARG | |
| Terephthalic Acid SCHEMBL27428746 | 0.93 | EGFR (0.44) | EGFRKMORARARARBRARG | |
| Terephthalic Acid SCHEMBL367109 | 0.93 | KMO (0.50) | EGFRKMORARARARBRARG | |
| Terephthalic Acid SCHEMBL3979457 | 0.86 | TSHR (0.50) | EGFRTSHRTP53RXRARXRB | |
| SCHEMBL5319785 | 0.85 | BCL2L1 (0.50) | EGFRTRIM24TRIM33TSHRTP53 | |
| Isophthalic Acid SCHEMBL8500503 | 0.84 | KMO (0.49) | EGFRKMOTRIM24TRIM33RXRA | |
| SCHEMBL9272984 | 0.84 | RARB (0.50) | EGFRRARARARBRARGTRIM24 | |
| Terephthalic Acid SCHEMBL5847732 | 0.84 | RARA (0.39) | EGFRKMORARARARBRARG | |
| SCHEMBL102784 | 0.84 | ITGB2 (0.38) | NPC1KMT2AFAAHNAAAALDH1A1 | |
| SCHEMBL14067104 | 0.84 | ITGB2 (0.38) | NPC1KMT2AFAAHNAAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 339 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11781008-B2 | Thermoplastic polyester elastomer resin composition for resin belt materials, and molded resin belt | TORAY CELANESE CO., LTD. (JP) | 2023-10-10 | — | — | US | claimed |
| US-11760840-B2 | Thermoplastic resin composition and molded article thereof | TEIJIN LIMITED (JP) | 2023-09-19 | — | — | US | claimed |
| US-11319436-B2 | Thermoplastic polyester resin composition and molded article | TORAY INDUSTRIES, INC. (JP) | 2022-05-03 | — | — | US | claimed |
| US-20200172726-A1 | THERMOPLASTIC POLYESTER RESIN COMPOSITION AND MOLDED ARTICLE | TORAY INDUSTRIES, INC. (JP) | 2020-06-04 | — | — | US | claimed |
| CN-106009544-B | A kind of polyester material and preparation method for nanometer injection molding with uniform surface | 广州辰东新材料有限公司 | 2018-09-07 | — | — | CN | claimed |
| CN-104629274-A | Polyester composite material for nano injection molding and preparation method thereof | GUANGZHOU CHENDONG NEW MATERIALS CO LTD | 2015-05-20 | — | — | CN | claimed |
| CN-104629273-A | Polyester composite material capable of being simultaneously applied to NMT technology and LDS technology and preparation method thereof | GUANGZHOU CHENDONG NEW MATERIALS CO LTD | 2015-05-20 | — | — | CN | claimed |
| EP-1580766-B1 | INSULATED WIRE AND RESIN DISPERSION | FURUKAWA ELECTRIC CO LTD (JP) | 2014-12-31 | — | — | EP | claimed |
| CN-100358730-C | Polyester film for high-sensitivity thermosensitive porous printing base paper | MITSUBISHI POLYESTER FILM CORP (JP) | 2008-01-02 | — | — | CN | claimed |
| CN-1069580-C | Composite resin film and metallic sheet coated with same | TOYO KOHAN CO LTD (JP) | 2001-08-15 | — | — | CN | claimed |
| CN-1228057-A | Composite resin film and composite resin-coated metal plate | TOYO KOHAN CO LTD (JP) | 1999-09-08 | — | — | CN | claimed |
| EP-0549188-B1 | Reinforced flame-retarded polyester resin compositions | GE PLASTICS JAPAN LTD (JP) | 1997-06-04 | — | — | EP | claimed |
| US-5326806-A | Reinforced flame-retardant polyester resin compositions | GENERAL ELECTRIC COMPANY (US) | 1994-07-05 | — | — | US | claimed |
| US-4011358-A | PRESSURE SENSITIVE ADHESIVE TAPES, LITHOGRAPHIC PRINTING PLATES, COATED ABRASIVES, SPLICING TAPES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1977-03-08 | — | — | US | claimed |
| JP-55128011-A | — | — | None | — | — | JP | disclosed |
| US-12040604-B2 | Composite reinforcement systems for power transmissionlines, and methods of forming same | Gridwrap, Inc. (US) | 2024-07-16 | — | — | US | disclosed |
| EP-4382562-A1 | INORGANIC FILLING MATERIAL AND INORGANIC FILLING MATERIAL-REINFORCED THERMOPLASTIC RESIN | Toray Industries, Inc. (JP) | 2024-06-12 | — | — | EP | disclosed |
| EP-0048483-A1 | Flame retarding polyester composition | TORAY INDUSTRIES, INC. (JP) | 1982-03-31 | — | — | EP | disclosed |
| JP-S55128011-A | STRETCH-BROKEN POLYESTER SLIVER AND ITS PRODUCTION | TORAY IND INC | 1980-10-03 | — | — | JP | disclosed |
| US-4170680-A | THERMOPLASTIC WEBS | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1979-10-09 | — | — | US | disclosed |