SCHEMBL3672358

SCHEMBL3672358

O=S(=O)(Oc1cccc(C(F)(F)C(F)(F)c2ccc(Oc3ccc(C(F)(F)C(F)(F)c4cccc(OS(=O)(=O)C(F)(F)F)c4)cc3)cc2)c1)C(F)(F)F

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 2/20 0.45
NR3C1 P04150 1/20 0.45
AR P10275 1/20 0.45
ESR2 Q92731 1/20 0.45
KIF11 P52732 1/20 0.41
CA1 P00915 3/20 0.40
CA2 P00918 3/20 0.40
CA9 Q16790 2/20 0.40
MAPK14 Q16539 1/20 0.40
PPARG P37231 1/20 0.38
PTPN1 P18031 1/20 0.38
NPC1 O15118 1/20 0.38
POLB P06746 1/20 0.38
CYP2C9 P11712 1/20 0.38
RAB9A P51151 1/20 0.38
SOS1 Q07889 1/20 0.37
DRD2 P14416 1/20 0.36
DRD1 P21728 1/20 0.36
DRD4 P21917 1/20 0.36
DRD5 P21918 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3672835 0.94 PGR (0.43) PGRNR3C1ARESR2KIF11
SCHEMBL3668197 0.94 PGR (0.43) PGRNR3C1ARESR2KIF11
SCHEMBL6058998 0.93 PGR (0.42) PGRNR3C1ARESR2KIF11
SCHEMBL3675923 0.87 PGR (0.41) PGRNR3C1ARESR2KIF11
SCHEMBL3671119 0.85 CA2 (0.47) PGRNR3C1ARESR2KIF11
SCHEMBL841583 0.84 CA1 (0.40) PGRNR3C1ARESR2KIF11
SCHEMBL5179650 0.82 CA1 (0.50) PGRNR3C1ARESR2CA1
SCHEMBL3740696 0.81 PGR (0.40) PGRNR3C1ARESR2KIF11
SCHEMBL3677839 0.81 PGR (0.40) PGRNR3C1ARESR2KIF11
SCHEMBL6938268 0.80 NR3C1 (0.48) PGRNR3C1ARESR2KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1329444-B1 Halogenated aromatic compound, (co)polymer thereof, and proton-conductive membrane comprising same JSR CORP (JP) 2010-05-05 EP disclosed
US-6933068-B2 Polymer electrolyte membrane and solid polymer electrolyte fuel cell using same HONDA GIKEN KOGYO KABUSHIKI KAISHA (JP) 2005-08-23 US disclosed
US-6833426-B2 A proton-conductive membrane containing the sulfonic acid group-containing polyarylene (co)polymer JSR CORPORATION (JP) 2004-12-21 US disclosed
US-6812290-B2 FOR USE AS ELECTROLYTES JSR CORPORATION (JP) 2004-11-02 US disclosed
US-20030195301-A1 Polyarylene copolymers and proton-conductive membrane JSR CORPORATION (JP) 2003-10-16 US disclosed
US-20030173547-A1 Halogenated aromatic compound, (co)polymer thereof, and proton-conductive membrane comprising same JSR CORPORATION (JP) 2003-09-18 US disclosed
EP-1329444-A1 Halogenated aromatic compound, (co)polymer thereof, and proton-conductive membrane comprising same JSR Corporation (JP) 2003-07-23 EP disclosed
US-20020172850-A1 Polymer electrolyte membrane and solid polymer electrolyte fuel cell using same HONDA GIKEN KOGYO KABUSHIKI KAISHA, JSR CORPORATION 2002-11-21 US disclosed
EP-1138712-A2 Polyarylene copolymers and proton-conductive membrane JSR Corporation (JP) 2001-10-04 EP disclosed