SCHEMBL3671594

SCHEMBL3671594

CCCc1ccc2cc(CC)ccc2c1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.64
CYP2A6 P11509 1/20 0.64
CNR1 P21554 1/20 0.48
CNR2 P34972 1/20 0.48
AKR1C3 P42330 1/20 0.46
AKR1C2 P52895 1/20 0.46
TRPA1 O75762 1/20 0.43
SIGMAR1 Q99720 1/20 0.41
BDKRB2 P30411 1/20 0.41
THRB P10828 1/20 0.40
LPL P06858 1/20 0.40
LIPG Q9Y5X9 1/20 0.40
TAAR1 Q96RJ0 1/20 0.39
NCEH1 Q6PIU2 2/20 0.39
DAO P14920 1/20 0.38
ALOX5 P09917 1/20 0.38
KDM4E B2RXH2 1/20 0.38
NPC1 O15118 1/20 0.38
LMNA P02545 1/20 0.38
TP53 P04637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31593166 0.93 CNR1 (0.54) CYP1A2CYP2A6CNR1CNR2SIGMAR1
SCHEMBL7193556 0.93 CNR1 (0.54) CYP1A2CYP2A6CNR1CNR2SIGMAR1
SCHEMBL347592 0.87 CYP2A6 (0.80) CYP1A2CYP2A6AKR1C3AKR1C2TRPA1
SCHEMBL29407167 0.87 CYP2A6 (0.80) CYP1A2CYP2A6AKR1C3AKR1C2TRPA1
SCHEMBL140016 0.84 CYP1A2 (0.68) CYP1A2CYP2A6CNR1CNR2SIGMAR1
SCHEMBL11694817 0.83 CYP1A2 (0.55) CYP1A2CYP2A6BDKRB2LPLLIPG
SCHEMBL6890734 0.82 CYP2A6 (0.73) CYP1A2CYP2A6AKR1C3AKR1C2TRPA1
SCHEMBL6885287 0.82 CYP2A6 (0.73) CYP1A2CYP2A6AKR1C3AKR1C2TRPA1
SCHEMBL17592414 0.82 ASIC3 (0.46) CYP1A2CYP2A6CNR1CNR2SIGMAR1
SCHEMBL3677920 0.82 CYP2A6 (0.56) CYP1A2CYP2A6CNR1CNR2SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100087676-A1 ENVIRONMENTALLY BENIGN AND SIMPLIFIED METHOD FOR PREPARATION OF AROMATIC DICARBOXYLIC ACID SAMSUNG PETROCHEMICAL CO., LTD. (KR) 2010-04-08 US disclosed
WO-2008111764-A1 ENVIRONMENTALLY BENIGN AND SIMPLIFIED METHOD FOR PREPARATION OF AROMATIC DICARBOXYLIC ACID SAMSUNG PETROCHEMICAL CO., LTD. (KR) 2008-09-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100087676-A1 ENVIRONMENTALLY BENIGN AND SIMPLIFIED METHOD FOR PREPARATION OF AROMATIC DICARBOXYLIC ACID DDC, HAO2, AOC1 CYP1A2 1404/4885CYP2A6 876/4885CNR1 2570/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.