SCHEMBL3671599

SCHEMBL3671599

CCC(C)Cc1ccc2ccccc2c1

nearest known ligand 0.65

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.65
HTR2C P28335 1/20 0.65
HTR2B P41595 1/20 0.65
CYP1A2 P05177 1/20 0.59
CYP2A6 P11509 1/20 0.59
SIGMAR1 Q99720 3/20 0.49
MME P08473 1/20 0.48
ACE P12821 1/20 0.48
CPA1 P15085 1/20 0.48
ACE2 Q9BYF1 1/20 0.48
NR3C1 P04150 1/20 0.46
PGR P06401 1/20 0.46
NR3C2 P08235 1/20 0.46
ADRB2 P07550 2/20 0.44
TACR1 P25103 2/20 0.43
MC4R P32245 1/20 0.43
MC5R P33032 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27309104 0.85 HTR2A (0.61) HTR2AHTR2CHTR2BCYP1A2CYP2A6
SCHEMBL8692161 0.83 HTR2A (0.62) HTR2AHTR2CHTR2BCYP1A2CYP2A6
SCHEMBL10500945 0.83 HTR2A (0.62) HTR2AHTR2CHTR2BCYP1A2CYP2A6
SCHEMBL3677922 0.82 HTR2A (0.71) HTR2AHTR2CHTR2BCYP1A2CYP2A6
SCHEMBL8689698 0.80 HTR2A (0.59) HTR2AHTR2CHTR2BCYP1A2CYP2A6
SCHEMBL13685120 0.80 HTR2A (0.59) HTR2AHTR2CHTR2BCYP1A2CYP2A6
SCHEMBL11884243 0.79 HTR2A (0.58) HTR2AHTR2CHTR2BCYP1A2CYP2A6
SCHEMBL2482281 0.79 HTR2A (0.58) HTR2AHTR2CHTR2BCYP1A2CYP2A6
SCHEMBL29292157 0.79 HTR2A (0.68) HTR2AHTR2CHTR2BCYP1A2CYP2A6
SCHEMBL6301138 0.78 HTR2A (0.67) HTR2AHTR2CHTR2BCYP1A2CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100087676-A1 ENVIRONMENTALLY BENIGN AND SIMPLIFIED METHOD FOR PREPARATION OF AROMATIC DICARBOXYLIC ACID SAMSUNG PETROCHEMICAL CO., LTD. (KR) 2010-04-08 US disclosed
WO-2008111764-A1 ENVIRONMENTALLY BENIGN AND SIMPLIFIED METHOD FOR PREPARATION OF AROMATIC DICARBOXYLIC ACID SAMSUNG PETROCHEMICAL CO., LTD. (KR) 2008-09-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100087676-A1 ENVIRONMENTALLY BENIGN AND SIMPLIFIED METHOD FOR PREPARATION OF AROMATIC DICARBOXYLIC ACID DDC, HAO2, AOC1 HTR2A 4288/4885HTR2C 4721/4885HTR2B 4658/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.