Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 12/20 | 0.49 |
| ▸ | S1PR3 | Q99500 | 12/20 | 0.49 |
| ▸ | S1PR2 | O95136 | 10/20 | 0.49 |
| ▸ | LPAR2 | Q9HBW0 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.45 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3673599 | 0.94 | HRH4 (0.55) | HRH4HRH3S1PR1S1PR3S1PR2 | |
| SCHEMBL3673106 | 0.94 | HRH4 (0.55) | HRH4HRH3S1PR1S1PR3S1PR2 | |
| SCHEMBL3671659 | 0.84 | SMN1; SMN2 (0.43) | SMN1; SMN2CYP1A2CYP2C19HDAC3HDAC8 | |
| SCHEMBL18828911 | 0.81 | S1PR1 (0.57) | HRH4HRH3S1PR1S1PR3S1PR2 | |
| SCHEMBL18636787 | 0.80 | HDAC3 (0.46) | HRH4HRH3S1PR1S1PR3S1PR2 | |
| SCHEMBL195630 | 0.79 | RARB (0.57) | — | |
| SCHEMBL15270260 | 0.78 | S1PR1 (0.57) | HRH4HRH3S1PR1S1PR3S1PR2 | |
| SCHEMBL3669489 | 0.77 | EPHX2 (0.45) | CA2CYP1A2CYP2C19HDAC3HDAC8 | |
| Hydrochloric Acid SCHEMBL16506887 | 0.77 | S1PR1 (0.56) | HRH4HRH3S1PR1S1PR3S1PR2 | |
| SCHEMBL10713905 | 0.76 | THRA (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642296-B2 | 2-hydroxy-1-(4-hydroxymethyl-phenyl)-2-methyl-propan-1-one, have higher reactivity at the benzylic hydroxy group and do not have a tendency to yellowing; photocurable composition for pigmented or non-pigmented varnish surface coatings | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2010-01-05 | — | — | US | disclosed |
| US-20070240609-A1 | Photoinitiators | IGM GROUP B.V. (NL) | 2007-10-18 | — | — | US | disclosed |
| EP-1763499-B1 | NEW PHOTOINITIATORS | CIBA SC HOLDING AG (CH) | 2007-09-26 | — | — | EP | disclosed |
| EP-1763499-A1 | NEW PHOTOINITIATORS | CIBA SPECIALTY CHEMICALS HOLDING INC. Patent Departement (CH) | 2007-03-21 | — | — | EP | disclosed |
| WO-2005100292-A1 | NEW PHOTOINITIATORS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2005-10-27 | — | — | WO | disclosed |