SCHEMBL3672391

SCHEMBL3672391

C=Cc1ccc(COCCN(CC)CC)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.47
POLB P06746 1/20 0.47
KMT2A Q03164 1/20 0.47
CYP1A2 P05177 1/20 0.39
LTA4H P09960 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
HTT P42858 1/20 0.39
BIRC5 O15392 1/20 0.38
CHRNB2 P17787 1/20 0.36
CHRNB4 P30926 1/20 0.36
CHRNA3 P32297 1/20 0.36
CHRNA7 P36544 1/20 0.36
CHRNA4 P43681 1/20 0.36
ALDH1A1 P00352 1/20 0.35
KCNH2 Q12809 1/20 0.35
PPARG P37231 1/20 0.35
HRH3 Q9Y5N1 1/20 0.35
MAOB P27338 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12860112 0.90 ALDH1A1 (0.41) MEN1POLBKMT2ACHRNB2CHRNB4
SCHEMBL3669858 0.86 MEN1 (0.46) MEN1POLBKMT2ACYP1A2LTA4H
SCHEMBL6749405 0.86 LYPLA1 (0.37) MEN1POLBKMT2ALTA4HCHRNB2
SCHEMBL188151 0.83 LYPLA1 (0.44) LTA4HCHRNB2CHRNB4CHRNA3CHRNA7
SCHEMBL3679381 0.83 ALDH1A1 (0.38) MEN1POLBKMT2ACHRNB2CHRNB4
SCHEMBL316823 0.81 ALDH1A1 (0.42) MEN1KMT2AHTTCHRNB2CHRNB4
SCHEMBL4757062 0.81 LYPLA1 (0.42) MEN1KMT2ALTA4HCHRNB2CHRNB4
SCHEMBL18832287 0.80 ALDH1A1 (0.50) POLBLTA4HCHRNB2CHRNB4CHRNA3
SCHEMBL12258256 0.80 PPARG (0.46) MEN1KMT2ACYP1A2CYP2D6CYP2C9
SCHEMBL7057892 0.80 AGXT (0.44) MEN1POLBKMT2ACYP1A2LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1298166-B1 RUBBER COMPOSITION JSR CORP (JP) 2007-02-21 EP claimed
US-6699935-B2 A CROSSLINKED RUBBER PARTICLES CONTAINING CONJUGATED DIENE MONOMER, AROMATIC VINYL MONOMER AND MONOMER WITH AT LEAST TWO POLYMERIZABLE UNSATURATED GROUPS DISPERSED IN A CONJUGATED DIENE/AROMATIC VINYL COPOLYMER; RESIST TO ROLLING, SKID, WEAR JSR CORPORATION (JP) 2004-03-02 US claimed
US-6653404-B2 Melt processability; dimensional stability JSR CORPORATION (JP) 2003-11-25 US claimed
US-20030125467-A1 A crosslinked rubber particles containing conjugated diene monomer, aromatic vinyl monomer and monomer with at least two polymerizable unsaturated groups dispersed in a conjugated diene/aromatic vinyl copolymer; resist to rolling, skid, wear JSR CORPORATION (JP) 2003-07-03 US claimed
EP-1298166-A1 RUBBER COMPOSITION JSR Corporation (JP) 2003-04-02 EP claimed
US-20010053813-A1 Rubber compositions JSR CORPORATION (JP) 2001-12-20 US claimed
EP-1152030-B1 Rubber mixtures based on crosslinked rubber particles and non-crosslinked rubbers JSR CORP (JP) 2012-12-12 EP disclosed
EP-1149867-B1 Crosslinked rubber particles and rubber compositions JSR CORP (JP) 2010-06-16 EP disclosed
US-7550536-B2 Acrylic rubber, process for its production, and rubber compositions, oil-and weather-resistant rubber compositions, and oil-and weather -resistant rubbers, containing the same JSR CORPORATION (JP) 2009-06-23 US disclosed
EP-1469018-B1 ACRYLIC RUBBER, PROCESS FOR ITS PRODUCTION, AND RUBBER COMPOSITIONS, OIL- AND WEATHER-RESISTANT RUBBER COMPOSITIONS, AND OIL- AND WEATHER-RESISTANT RUBBERS, CONTAINING THE SAME JSR CORP (JP) 2009-06-10 EP disclosed
US-20080081873-A1 Thermoplastic Elastomer Composition And Method For Producing Same JSR CORPORATION (JP) 2008-04-03 US disclosed
EP-1201368-B1 Polishing pad comprising a water-insoluble substance and method for producing thereof JSR CORP (JP) 2008-01-16 EP disclosed
EP-1535960-B1 Oil resistant and weather resistant rubber composition and molded product using the same JSR CORP (JP) 2007-10-24 EP disclosed
US-20020045691-A1 Conjugated diene-based rubber, oil extended rubber and rubber composition containing the same JSR CORPORATION (JP) 2002-04-18 US disclosed
EP-1184415-A2 Conjugated diene-based rubber, oil extended rubber and rubber composition containing the same JSR Corporation (JP) 2002-03-06 EP disclosed
US-20020007011-A1 Crosslinked rubber particles and rubber compositions JSR CORPORATION (JP) 2002-01-17 US disclosed
US-20010053813-A1 Rubber compositions JSR CORPORATION (JP) 2001-12-20 US disclosed
EP-1152030-A2 Rubber mixtures based on crosslinked rubber particles and non-crosslinked rubbers JSR Corporation (JP) 2001-11-07 EP disclosed
EP-1149866-A2 Rubber mixtures based on crosslinked rubber particles and non-crosslinked rubbers JSR Corporation (JP) 2001-10-31 EP disclosed
EP-1149867-A2 Crosslinked rubber particles and rubber compositions JSR Corporation (JP) 2001-10-31 EP disclosed