Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LYPLA1 | O75608 | 1/20 | 0.37 |
| ▸ | LYPLA2 | O95372 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL188151 | 0.89 | LYPLA1 (0.44) | LYPLA1LYPLA2KDM4ECHRNB2CHRNB4 | |
| SCHEMBL3679381 | 0.89 | ALDH1A1 (0.38) | MEN1POLBKMT2ACHRNB2CHRNB4 | |
| SCHEMBL3672391 | 0.86 | MEN1 (0.47) | MEN1POLBKMT2ACHRNB2CHRNB4 | |
| SCHEMBL4757062 | 0.86 | LYPLA1 (0.42) | LYPLA1LYPLA2MEN1KMT2AKDM4E | |
| SCHEMBL12860112 | 0.79 | ALDH1A1 (0.41) | LYPLA1LYPLA2MEN1POLBKMT2A | |
| SCHEMBL2231132 | 0.79 | ALDH1A1 (0.41) | LYPLA1LYPLA2MEN1KMT2ACHRNB2 | |
| SCHEMBL3668335 | 0.77 | CHRNB2 (0.36) | MEN1POLBKMT2ACHRNB2CHRNB4 | |
| SCHEMBL9670428 | 0.75 | LYPLA1 (0.54) | LYPLA1LYPLA2CHRNB2CHRNA4HRH3 | |
| SCHEMBL3672602 | 0.75 | HRH3 (0.45) | KDM4ECHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL16840077 | 0.74 | PPARG (0.34) | LYPLA1LYPLA2KDM4ECHRNB2CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699935-B2 | A CROSSLINKED RUBBER PARTICLES CONTAINING CONJUGATED DIENE MONOMER, AROMATIC VINYL MONOMER AND MONOMER WITH AT LEAST TWO POLYMERIZABLE UNSATURATED GROUPS DISPERSED IN A CONJUGATED DIENE/AROMATIC VINYL COPOLYMER; RESIST TO ROLLING, SKID, WEAR | JSR CORPORATION (JP) | 2004-03-02 | — | — | US | disclosed |
| US-20030125467-A1 | A crosslinked rubber particles containing conjugated diene monomer, aromatic vinyl monomer and monomer with at least two polymerizable unsaturated groups dispersed in a conjugated diene/aromatic vinyl copolymer; resist to rolling, skid, wear | JSR CORPORATION (JP) | 2003-07-03 | — | — | US | disclosed |