⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2933105 | 0.80 | TGM2 (0.36) | — | |
| SCHEMBL22635787 | 0.79 | TSHR (0.39) | — | |
| SCHEMBL21409812 | 0.79 | TSHR (0.39) | — | |
| SCHEMBL22635788 | 0.79 | — | — | |
| SCHEMBL976113 | 0.74 | — | — | |
| SCHEMBL27961654 | 0.74 | ALDH1A1 (0.43) | — | |
| SCHEMBL21943739 | 0.74 | TGM2 (0.35) | — | |
| SCHEMBL26705 | 0.72 | — | — | |
| SCHEMBL7101115 | 0.72 | ALDH1A1 (0.46) | — | |
| SCHEMBL28652020 | 0.72 | THRB (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118420485-A | Preparation method of gem-difluoro olefin derivative | 广东医科大学 | 2024-08-02 | — | — | CN | claimed |
| CN-118420485-A | Preparation method of gem-difluoro olefin derivative | 广东医科大学 | 2024-08-02 | — | — | CN | disclosed |
| CN-118420485-A | Preparation method of gem-difluoro olefin derivative | 广东医科大学 | 2024-08-02 | — | — | CN | disclosed |
| CN-117820065-A | Gamma-aryl substituted gem-difluoro olefin compound and preparation method thereof | 湖南大学 | 2024-04-05 | — | — | CN | disclosed |
| CN-111698946-B | Acoustic lens, acoustic probe, acoustic wave, and related resin material, measurement device, diagnostic device, endoscope, and manufacturing method | 富士胶片株式会社 | 2023-07-18 | — | — | CN | disclosed |
| CN-216677758-U | Composite porous filtering membrane and filter | 恩特格里斯公司 | 2022-06-07 | — | — | CN | disclosed |
| CN-113828164-A | Composite filter media | 恩特格里斯公司 | 2021-12-24 | — | — | CN | disclosed |
| CN-111698946-A | Resin material for acoustic probe, acoustic lens, acoustic probe, acoustic measurement device, ultrasonic diagnostic device, photoacoustic measurement device, ultrasonic endoscope, and method for manufacturing acoustic lens | 富士胶片株式会社 | 2020-09-22 | — | — | CN | disclosed |
| WO-2019188426-A1 | ACOUSTIC WAVE PROBE RESIN MATERIAL, ACOUSTIC LENS, ACOUSTIC WAVE PROBE, ACOUSTIC WAVE MEASURING APPARATUS, ULTRASONIC DIAGNOSTIC APPARATUS, PHOTOACOUSTIC WAVE MEASURING APPARATUS, ULTRASONIC ENDOSCOPE, AND METHOD FOR MANUFACTURING ACOUSTIC LENS | 富士フイルム株式会社 | 2019-10-03 | — | — | WO | disclosed |
| EP-2139874-A2 | ISOXAZOLINE COMPOUNDS AND THEIR USE IN PEST CONTROL | Sumitomo Chemical Company, Limited (JP) | 2010-01-06 | — | — | EP | disclosed |
| WO-2008126665-A2 | ISOXAZOLINE COMPOUNDS AND THEIR USE IN PEST CONTROL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-10-23 | — | — | WO | disclosed |