Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | S100B | P04271 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3675442 | 0.83 | NOS2 (0.39) | NOS2CYP3A4TSHRPIK3CA | |
| SCHEMBL3678897 | 0.82 | ALDH1A1 (0.33) | NOS3NOS2CYP3A4TSHRALDH1A1 | |
| SCHEMBL9847085 | 0.81 | CYP3A4 (0.43) | NOS3NOS2CYP3A4TSHRPIK3CA | |
| SCHEMBL2954428 | 0.77 | NOS2 (0.42) | NOS3NOS2CYP3A4TSHRPIK3CA | |
| SCHEMBL3668718 | 0.76 | SKP2 (0.44) | NOS3NOS2POLBSMN1; SMN2 | |
| SCHEMBL3222203 | 0.76 | ALDH1A1 (0.39) | NOS3NOS2CYP3A4TSHRPIK3CA | |
| SCHEMBL30117633 | 0.75 | NOS3 (0.41) | NOS3NOS2CYP3A4TSHRPIK3CA | |
| SCHEMBL215981 | 0.75 | NOS3 (0.41) | NOS3NOS2CYP3A4TSHRPIK3CA | |
| SCHEMBL3671141 | 0.75 | NOS2 (0.35) | NOS2POLB | |
| SCHEMBL14159898 | 0.74 | NOS3 (0.35) | NOS3NOS2CYP3A4TSHRPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1426392-B1 | COMPOSITION FOR OPTICAL MATERIAL | MITSUBISHI GAS CHEMICAL CO (JP) | 2010-02-24 | — | — | EP | disclosed |
| US-6960640-B2 | Composition for optical material | MITSUBISHI GAS CHEMICAL CO., LTD. (JP) | 2005-11-01 | — | — | US | disclosed |
| US-20040147708-A1 | Composition for optical material | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2004-07-29 | — | — | US | disclosed |
| EP-1426392-A1 | COMPOSITION FOR OPTICAL MATERIAL | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2004-06-09 | — | — | EP | disclosed |