Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.46 |
| ▸ | SRC | P12931 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.37 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL367569 | 0.89 | SRC (0.46) | EGFRSRCALDH1A1HPGDKMT2A | |
| SCHEMBL367764 | 0.89 | EGFR (0.45) | EGFRSRCALDH1A1HPGDNPC1 | |
| SCHEMBL366876 | 0.87 | EGFR (0.44) | EGFRSRCALDH1A1HPGDKMT2A | |
| SCHEMBL365259 | 0.87 | KDM4E (0.44) | EGFRSRCALDH1A1HPGDHTR2A | |
| Potassium Ion SCHEMBL364867 | 0.84 | ALDH1A1 (0.40) | EGFRSRCALDH1A1HPGDNPC1 | |
| SCHEMBL366442 | 0.83 | ALDH1A1 (0.42) | EGFRSRCALDH1A1HPGDNPC1 | |
| SCHEMBL364281 | 0.83 | NR4A2 (0.48) | EGFRSRCALDH1A1KMT2APOLB | |
| SCHEMBL365635 | 0.82 | IDO1 (0.44) | EGFRSRCALDH1A1HPGDNPC1 | |
| SCHEMBL364389 | 0.82 | ALDH1A1 (0.48) | EGFRSRCALDH1A1HPGDNPC1 | |
| SCHEMBL366978 | 0.81 | SCN9A (0.45) | ALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |