Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MLYCD | O95822 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL365912 | 0.88 | CES1 (0.45) | IDO1HTTCES1EGFRSRC | |
| SCHEMBL367764 | 0.86 | EGFR (0.45) | HTTEGFRSRCKDM4EHTR2A | |
| SCHEMBL367091 | 0.83 | KMT2A (0.44) | HTTEGFRSRCKDM4EELANE | |
| SCHEMBL365259 | 0.83 | KDM4E (0.44) | EGFRSRCKDM4EHTR2AHTR2C | |
| SCHEMBL367330 | 0.82 | EGFR (0.46) | EGFRSRCKDM4EHTR2AHTR2C | |
| SCHEMBL365634 | 0.79 | CES1 (0.38) | IDO1HTTCES1EGFRSRC | |
| SCHEMBL366000 | 0.78 | ELANE (0.47) | HTTELANEALDH1A1LMNA | |
| SCHEMBL365000 | 0.77 | HTT (0.42) | IDO1HTTCES1KDM4EELANE | |
| SCHEMBL366811 | 0.77 | EGFR (0.44) | EGFRSRCKDM4EELANENPC1 | |
| SCHEMBL367201 | 0.77 | EGFR (0.45) | EGFRSRCKDM4EHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |