Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3669311 | 0.90 | CFB (0.36) | P2RX7CFB | |
| SCHEMBL3674513 | 0.86 | P2RX7 (0.42) | P2RX7 | |
| SCHEMBL3804488 | 0.83 | TAAR1 (0.40) | P2RX7CFB | |
| SCHEMBL3671172 | 0.78 | CFB (0.36) | CFB | |
| SCHEMBL3668500 | 0.77 | CFB (0.35) | CFB | |
| SCHEMBL3672714 | 0.75 | IDH1 (0.32) | — | |
| SCHEMBL3670065 | 0.75 | TAAR1 (0.38) | P2RX7CFB | |
| SCHEMBL12637702 | 0.75 | CFB (0.33) | P2RX7CFB | |
| SCHEMBL3411857 | 0.75 | CFB (0.36) | P2RX7CFB | |
| SCHEMBL3433522 | 0.74 | CFB (0.41) | CFB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2242753-A1 | OXAZOLIDINE AND THIAZOLIDINE SELECTIVE SUBTYPE ALPHA 2 ADRENERGIC AGENTS AND METHODS FOR USE THEREOF | ALLERGAN, INC. (US) | 2010-10-27 | — | — | EP | disclosed |
| WO-2009091760-A1 | OXAZOLIDINE AND THIAZOLIDINE SELECTIVE SUBTYPE ALPHA 2 ADRENERGIC AGENTS AND METHODS FOR USE THEREOF | ALLERGAN, INC. (US) | 2009-07-23 | — | — | WO | disclosed |