Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3665641 | 0.90 | ADRA2A (0.33) | IDH1 | |
| SCHEMBL3671320 | 0.83 | TAAR1 (0.40) | — | |
| SCHEMBL3670065 | 0.75 | TAAR1 (0.38) | — | |
| SCHEMBL3673459 | 0.75 | P2RX7 (0.41) | — | |
| SCHEMBL3672711 | 0.75 | GRIN1 (0.33) | IDH1 | |
| SCHEMBL3411857 | 0.75 | CFB (0.36) | — | |
| SCHEMBL3669311 | 0.73 | CFB (0.36) | — | |
| SCHEMBL3804488 | 0.71 | TAAR1 (0.40) | — | |
| SCHEMBL3674513 | 0.69 | P2RX7 (0.42) | — | |
| SCHEMBL3668500 | 0.69 | CFB (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2240468-A1 | SELECTIVE SUBTYPE ALPHA 2 ADRENERGIC AGENTS AND METHODS FOR USE THEREOF | ALLERGAN, INC. (US) | 2010-10-20 | — | — | EP | disclosed |
| WO-2009091759-A1 | SELECTIVE SUBTYPE ALPHA 2 ADRENERGIC AGENTS AND METHODS FOR USE THEREOF | ALLERGAN, INC. (US) | 2009-07-23 | — | — | WO | disclosed |