SCHEMBL367356

SCHEMBL367356

c1ccc(CCC2(c3ccccc3)CCCCC2)cc1

nearest known ligand 0.60

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.57
SLC6A4 P31645 4/20 0.55
SLC6A2 P23975 3/20 0.55
SLC6A3 Q01959 3/20 0.55
MEN1 O00255 1/20 0.54
KMT2A Q03164 1/20 0.54
CYP3A4 P08684 1/20 0.53
CYP2C19 P33261 1/20 0.53
S1PR1 P21453 3/20 0.51
S1PR3 Q99500 1/20 0.51
OPRM1 P35372 2/20 0.46
OPRL1 P41146 2/20 0.46
MAOA P21397 1/20 0.45
MAOB P27338 1/20 0.45
TAAR1 Q96RJ0 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25341004 0.94 DPP4 (0.53) DPP4SLC6A4SLC6A2SLC6A3MEN1
SCHEMBL49169 0.82 DPP4 (0.59) DPP4SLC6A4SLC6A2SLC6A3MEN1
SCHEMBL17208745 0.80 SLC6A4 (0.59) DPP4SLC6A4SLC6A2SLC6A3S1PR1
SCHEMBL2089640 0.80 SLC6A4 (0.59) DPP4SLC6A4SLC6A2SLC6A3S1PR1
SCHEMBL2864514 0.80 DPP4 (0.68) DPP4SLC6A4SLC6A2SLC6A3S1PR1
SCHEMBL5267941 0.79 DPP4 (0.61) DPP4SLC6A4SLC6A2SLC6A3MEN1
Hydrochloric Acid SCHEMBL10669389 0.78 DPP4 (0.66) DPP4SLC6A4SLC6A2SLC6A3S1PR1
SCHEMBL25339455 0.78 OPRM1 (0.47) MEN1KMT2AS1PR1S1PR3OPRM1
SCHEMBL25340627 0.78 OPRM1 (0.46) DPP4SLC6A4SLC6A2SLC6A3MEN1
SCHEMBL10208913 0.78 DPP4 (0.70) DPP4SLC6A4SLC6A2SLC6A3S1PR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1201182-C Liquid crystal display contg. chiral dopant MERCK PATENT GMBH (DE) 2005-05-11 CN claimed
CN-1420382-A Liquid crystal display contg. chiral dopant MERCK PATENT GMBH (DE) 2003-05-28 CN claimed
US-10982149-B2 Chiral compounds MERCK PATENT GMBH (DE) 2021-04-20 US disclosed
US-10793776-B2 Compositions comprising functionalized polyvinyl alcohol and nanocapsules containing a liquid crystalline medium MERCK PATENT GMBH (DE) 2020-10-06 US disclosed
EP-3467074-B1 COMPOSITIONS COMPRISING FUNCTIONALIZED POLYVINYL ALCOHOL AND NANOCAPSULES CONTAINING A LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2020-07-01 EP disclosed
EP-3443050-B1 COMPOSITION FOR NANOENCAPSULATION AND NANOCAPSULES COMPRISING A LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2020-01-29 EP disclosed
EP-3359625-B1 CHIRAL COMPOUNDS MERCK PATENT GMBH (DE) 2019-10-23 EP disclosed
CN-110325522-A Liquid crystal compounds 默克专利股份有限公司 2019-10-11 CN disclosed
CN-109996791-A Single fluorination hexamethylene 默克专利股份有限公司 2019-07-09 CN disclosed
US-20190127642-A1 COMPOSITION FOR NANOENCAPSULATION AND NANOCAPSULES COMPRISING A LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2019-05-02 US disclosed
US-20190106627-A1 COMPOSITIONS COMPRISING FUNCTIONALIZED POLYVINYL ALCOHOL AND NANOCAPSULES CONTAINING A LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2019-04-11 US disclosed
CN-1172496-A Electro-optic liquid crystal display MERCK PATENT GMBH (DE) 1998-02-04 CN disclosed
EP-0230920-B1 FLUID FOR TRACTION DRIVE IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-01-08 EP disclosed
EP-0441951-A1 HALOGENATED BENZENE DERIVATIVES AND LIQUID CRYSTALLINE MEDIUM. MERCK PATENT GMBH (DE) 1991-08-21 EP disclosed
WO-1991003445-A2 HALOGENATED BENZENE DERIVATIVES AND LIQUID CRYSTALLINE MEDIUM MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1991-03-21 WO disclosed
CN-1040024-A 2, the 3-Difluorophenol derivatives MERCK PATENT GMBH (DE) 1990-02-28 CN disclosed
EP-0332024-A1 Heterocyclic derivatives of 1,2-difluorobenzene MERCK PATENT GmbH (DE) 1989-09-13 EP disclosed
EP-0332007-A1 Derivatives of 2,3-difluorohydroquinone MERCK PATENT GmbH (DE) 1989-09-13 EP disclosed
US-4704490-A SYNERGISTIC MIXTURE OF ALICYCLIC HYDROCARBONS IDEMITSU KOSAN COMPANY, LIMITED (JP) 1987-11-03 US disclosed
EP-0230920-A2 Fluid for traction drive IDEMITSU KOSAN COMPANY LIMITED (JP) 1987-08-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10982149-B2 Chiral compounds FANCI, COL1A1, LCP1 DPP4 3621/4885SLC6A4 3604/4885SLC6A2 3009/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.