Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL49169 | 0.98 | DPP4 (0.59) | DPP4SLC6A4SLC6A2SLC6A3MEN1 | |
| SCHEMBL10606332 | 0.96 | DPP4 (0.55) | DPP4SLC6A4SLC6A2SLC6A3MEN1 | |
| SCHEMBL9618804 | 0.85 | ADRB2 (0.50) | DPP4SLC6A4SLC6A2SLC6A3MEN1 | |
| SCHEMBL29386486 | 0.85 | SLC6A3 (0.59) | DPP4SLC6A4SLC6A2SLC6A3OPRM1 | |
| SCHEMBL9741797 | 0.83 | MAOA (0.45) | DPP4SLC6A4SLC6A2SLC6A3MEN1 | |
| SCHEMBL1169437 | 0.83 | DPP4 (0.43) | DPP4SLC6A4SLC6A2SLC6A3MEN1 | |
| SCHEMBL367356 | 0.79 | DPP4 (0.57) | DPP4SLC6A4SLC6A2SLC6A3MEN1 | |
| SCHEMBL12982312 | 0.78 | MAOA (0.44) | DPP4SLC6A4SLC6A2SLC6A3MAOA | |
| SCHEMBL12982717 | 0.78 | KDM1A (0.45) | DPP4SLC6A4SLC6A2SLC6A3MAOA | |
| SCHEMBL25341004 | 0.77 | DPP4 (0.53) | DPP4SLC6A4SLC6A2SLC6A3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1697371-B1 | AZABICYCLIC HETEROCYCLES AS CANNABINOID RECEPTOR MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2007-04-25 | — | — | EP | claimed |
| EP-1697370-B1 | AZABICYCLIC HETEROCYCLES AS CANNABINOID RECEPTOR MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2007-04-25 | — | — | EP | claimed |