Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL3673750

CC(C)O.CCCCCC.O=C(O)C(F)(F)F

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
FAAH O00519 8/20 0.52
CES2 O00748 6/20 0.50
CES1 P23141 5/20 0.50
MEN1 O00255 1/20 0.50
CYP1A2 P05177 1/20 0.50
KMT2A Q03164 1/20 0.50
HSD17B10 Q99714 1/20 0.50
EPHX1 P07099 1/20 0.45
GPR84 Q9NQS5 3/20 0.45
FFAR1 O14842 1/20 0.45
MAPT P10636 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Heptane SCHEMBL3918420 0.98 FAAH (0.54) FAAHCES2CES1MEN1CYP1A2
Trifluoroacetic Acid SCHEMBL28128351 0.98 FAAH (0.50) FAAHCES2CES1MEN1CYP1A2
Decane SCHEMBL6353937 0.98 FAAH (0.54) FAAHCES2CES1MEN1CYP1A2
Trifluoroacetic Acid SCHEMBL28015086 0.96 FAAH (0.48) FAAHCES2CES1MEN1CYP1A2
Heptane SCHEMBL7647372 0.94 FAAH (0.50) FAAHCES2CES1MEN1CYP1A2
Trifluoroacetic Acid SCHEMBL3273685 0.90 FAAH (0.61) FAAHCES2CES1MEN1CYP1A2
Trifluoroacetic Acid SCHEMBL5238463 0.90 FAAH (0.44) FAAHCES2CES1MEN1CYP1A2
Trifluoroacetic Acid SCHEMBL28562828 0.88 FAAH (0.42) FAAHCES2CES1MEN1CYP1A2
Octane SCHEMBL1696265 0.87 FAAH (0.62) FAAHCES2CES1MEN1CYP1A2
Decane SCHEMBL3416451 0.87 FAAH (0.62) FAAHCES2CES1MEN1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 122 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116429927-A Method for analyzing content of enantiomer in N-formyl-L-leucine 大邦(湖南)生物制药有限公司 2023-07-14 CN claimed
CN-116297921-A Isomer detection method of tedizolid phosphate intermediate 成都美域高制药有限公司 2023-06-23 CN claimed
CN-114324702-A Isomer detection method of carfilzomib intermediate 南京格亚医药科技有限公司 2022-04-12 CN claimed
CN-112557566-A Method for detecting corresponding isomer of mitiglinide calcium intermediate S-benzylsuccinic acid 江西济民可信药业有限公司 2021-03-26 CN claimed
CN-112461985-A Method for detecting malic acid isomer 四川太平洋药业有限责任公司 2021-03-09 CN claimed
CN-107688069-B Method for detecting (1R,2R) -cyclohexane-1, 2-dimethanol 顾世海 2020-11-03 CN claimed
CN-109142585-B Method for detecting isomer of sodium pantothenate 珠海润都制药股份有限公司 2020-06-05 CN claimed
CN-109142585-A A kind of detection method of sodium pantothenate isomers 珠海润都制药股份有限公司 2019-01-04 CN claimed
CN-104535673-B A kind of method of HPLC separation determination rosuvastain calcium enantiomter SUNSHINE LAKE PHARMA CO.,LTD. (CN) 2016-04-20 CN claimed
CN-104535673-A Method for separating and measuring enantiomer of rosuvastatin calcium via HPLC GUANGDONG HEC PHARMACEUTICAL 2015-04-22 CN claimed
US-20240238265-A1 ADAMANTANE AMIDES AND THIOAMIDES FOR THE TREATMENT OF EBOLAVIRUS INFECTION ARISAN THERAPEUTICS INC. (US) 2024-07-18 US disclosed
CN-118222650-A Method for synthesizing itramod through asymmetric esterification 安徽艾立德制药有限公司 2024-06-21 CN disclosed
CN-117451900-A Analysis method of threonine protected amino acid 苏州正济药业有限公司 2024-01-26 CN disclosed
CN-117430547-A Preparation method of single enantiomer of tetrahydrocyclopenta [ b ] indol-3-yl acetic acid and derivative thereof 安徽艾立德制药有限公司 2024-01-23 CN disclosed
CN-116769687-A Recombinant escherichia coli for producing L-phenyllactic acid as well as construction method and application thereof 大邦(湖南)生物制药有限公司 2023-09-19 CN disclosed
EP-0700395-B1 INDOLE DERIVATIVES AS STEROID 5-ALPHA-REDUCTASE INHIBITORS PFIZER LTD (GB) 1997-06-11 EP disclosed
EP-0700395-A1 INDOLE DERIVATIVES AS STEROID 5-g(a)-REDUCTASE INHIBITORS PFIZER LTD (GB) 1996-03-13 EP disclosed
EP-0671975-A1 CHIRAL ADSORBENTS AND PREPARATION THEREOF AS WELL AS COMPOUNDS ON WHICH THE ADSORBENTS ARE BASED AND PREPARATION OF THESE COMPOUNDS Eka Chemicals AB (SE) 1995-09-20 EP disclosed
WO-1994027990-A1 INDOLE DERIVATIVES AS STEROID 5α-REDUCTASE INHIBITORS PFIZER LIMITED (GB) 1994-12-08 WO disclosed
WO-1994012275-A1 CHIRAL ADSORBENTS AND PREPARATION THEREOF AS WELL AS COMPOUNDS ON WHICH THE ADSORBENTS ARE BASED AND PREPARATION OF THESE COMPOUNDS EKA NOBEL AB (SE) 1994-06-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240238265-A1 ADAMANTANE AMIDES AND THIOAMIDES FOR THE TREATMENT OF EBOLAVIRUS INFECTION IFNAR1, NR4A3, NR0B2 FAAH 3374/4885CES2 2305/4885CES1 3440/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.