SCHEMBL3673954

SCHEMBL3673954

C=C(C)C(=O)OC(C)n1c2ccccc2c2ccccc21

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.43
HTT P42858 2/20 0.41
NPY5R Q15761 2/20 0.39
KDM4E B2RXH2 3/20 0.38
ELANE P08246 5/20 0.38
F2 P00734 1/20 0.38
PLAU P00749 1/20 0.38
ALDH1A1 P00352 1/20 0.37
HPGD P15428 1/20 0.37
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
MAPT P10636 2/20 0.34
LMNA P02545 1/20 0.34
KAT2B Q92831 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11209620 0.83 POLB (0.48) POLBHTTNPY5RKDM4EELANE
SCHEMBL3673989 0.78 POLB (0.40) POLBHTTNPY5RKDM4EELANE
SCHEMBL11772571 0.78 ALDH1A1 (0.49) KDM4EALDH1A1HPGDMAPTLMNA
SCHEMBL8578110 0.74 TSHR (0.39) ALDH1A1KMT2A
SCHEMBL8386184 0.74 PTPN1 (0.37) POLBHTTNPY5RKDM4EELANE
SCHEMBL7073898 0.73 POLB (0.48) POLBHTTKDM4EELANEALDH1A1
SCHEMBL2030887 0.72 LMNA (0.46) POLBHTTALDH1A1KMT2AMAPT
SCHEMBL24589423 0.71 POLB (0.44) POLBHTTNPY5RKDM4EALDH1A1
SCHEMBL27841871 0.71 POLB (0.53) POLBHTTNPY5RKDM4EALDH1A1
SCHEMBL21792682 0.70 GPR3 (0.44) POLBHTTNPY5RKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2139929-B1 POLYCARBAZOLYL(METH)ACRYLATE LIGHT EMISSIVE COMPOSITIONS GEN ELECTRIC (US) 2014-10-08 EP disclosed
EP-2139929-A1 POLYCARBAZOLYL(METH)ACRYLATE LIGHT EMISSIVE COMPOSITIONS General Electric Company (US) 2010-01-06 EP disclosed
WO-2008130805-A1 POLYCARBAZOLYL(METH)ACRYLATE LIGHT EMISSIVE COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 2008-10-30 WO disclosed
US-20080258111-A1 POLYCARBAZOLYL(METH)ACRYLATE LIGHT EMISSIVE COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 2008-10-23 US disclosed