SCHEMBL3673989

SCHEMBL3673989

C=CC(=O)OC(C)n1c2ccccc2c2ccccc21

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.40
NPY5R Q15761 2/20 0.39
KDM4E B2RXH2 3/20 0.38
HTT P42858 2/20 0.38
ELANE P08246 3/20 0.38
F2 P00734 1/20 0.38
PLAU P00749 1/20 0.38
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
ALDH1A1 P00352 4/20 0.35
HPGD P15428 2/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
TSHR P16473 1/20 0.35
CYP2C19 P33261 1/20 0.35
MAPT P10636 3/20 0.34
LMNA P02545 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17224376 0.82 TSPO (0.37) NPY5RKDM4EMEN1KMT2AALDH1A1
SCHEMBL11209620 0.80 POLB (0.48) POLBNPY5RKDM4EHTTELANE
SCHEMBL3673954 0.78 POLB (0.43) POLBNPY5RKDM4EHTTELANE
SCHEMBL11798343 0.78 BACE1 (0.46) KDM4EALDH1A1HPGDCYP1A2CYP3A4
SCHEMBL1416445 0.76 THRB (0.48) POLBKDM4EHTTKMT2AALDH1A1
SCHEMBL8741369 0.75 GPR3 (0.39) POLBNPY5RKDM4EHTTMEN1
SCHEMBL476933 0.74 TSHR (0.39) HPGDTSHR
SCHEMBL2033573 0.72 LMNA (0.46) POLBHTTKMT2AALDH1A1SMN1; SMN2
SCHEMBL2357061 0.71 POLB (0.41) POLBKDM4EHTTMEN1KMT2A
Acrylic Acid Methyl Ester SCHEMBL15637919 0.71 POLB (0.42) POLBKDM4EHTTELANEF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2139929-A1 POLYCARBAZOLYL(METH)ACRYLATE LIGHT EMISSIVE COMPOSITIONS General Electric Company (US) 2010-01-06 EP disclosed
WO-2008130805-A1 POLYCARBAZOLYL(METH)ACRYLATE LIGHT EMISSIVE COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 2008-10-30 WO disclosed