Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5066935 | 0.80 | ALDH1A1 (0.55) | ALDH1A1MAPTTDP1KMT2ATSHR | |
| SCHEMBL5040591 | 0.79 | CA2 (0.56) | ALDH1A1HRH3LMNAKMT2A | |
| SCHEMBL15505262 | 0.79 | ALDH1A1 (0.39) | ALDH1A1MAPTNPC1TDP1KMT2A | |
| SCHEMBL14944204 | 0.78 | AKR1B10 (0.42) | ALDH1A1MAPTTDP1PSMD14LMNA | |
| SCHEMBL22966052 | 0.78 | ALB (0.47) | ALDH1A1FFAR1PPARGPPARDPPARA | |
| SCHEMBL18868404 | 0.77 | ALDH1A1 (0.46) | ALDH1A1NPC1TDP1PSMD14LMNA | |
| SCHEMBL21068905 | 0.77 | HRH3 (0.43) | ALDH1A1HRH3PPARGPPARAGRM5 | |
| SCHEMBL27374394 | 0.77 | ALDH1A1 (0.46) | ALDH1A1PPARGMAPTNPC1TDP1 | |
| SCHEMBL14378813 | 0.77 | TSHR (0.62) | ALDH1A1TSHR | |
| SCHEMBL8421683 | 0.77 | FFAR1 (0.49) | ALDH1A1FFAR1PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170136450-A1 | POLYMER CONTAINING CARBOXYL GROUP, PREPARATION METHOD AND APPLICATION THEREOF, SUPPORTED CATALYST AND PREPARATION METHODS THEREOF AND PREPARATION METHODS OF PENEM ANTIBIOTIC INTERMEDIATE | ASYMCHEM LABORATORIES (FUXIN) CO., LTD. (CN) | 2017-05-18 | — | — | US | disclosed |
| US-8273802-B2 | Silicones formed from an oxygen permeable component and a vinyl carbonate, carbamate ester or amide beta-substituted vinyl pyrrolidone; improve wettability of the lens without a surface treatment | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2012-09-25 | — | — | US | disclosed |
| EP-1890171-B1 | Wettable hydrogels comprising reactive, hydrophilic, polymeric internal wetting agents | JOHNSON & JOHNSON VISION CARE (US) | 2010-12-22 | — | — | EP | disclosed |
| US-20080275156-A1 | WETTABLE HYDROGELS COMPRISING REACTIVE, HYDROPHILIC, POLYMERIC INTERNAL WETTING AGENTS | JOHNSON & JOHNSON VISION CARE, INC. | 2008-11-06 | — | — | US | disclosed |
| EP-1800150-B1 | WETTABLE HYDROGELS COMPRISING REACTIVE, HYDROPHILIC, POLYMERIC INTERNAL WETTING AGENTS | JOHNSON & JOHNSON VISION CARE (US) | 2008-08-06 | — | — | EP | disclosed |
| EP-1890171-A2 | Wettable hydrogels comprising reactive, hydrophilic, polymeric internal wetting agents | Johnson & Johnson Vision Care, Inc. (US) | 2008-02-20 | — | — | EP | disclosed |
| US-7249848-B2 | Wettable hydrogels comprising reactive, hydrophilic, polymeric internal wetting agents | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2007-07-31 | — | — | US | disclosed |
| EP-1800150-A1 | WETTABLE HYDROGELS COMPRISING REACTIVE, HYDROPHILIC, POLYMERIC INTERNAL WETTING AGENTS | Johnson & Johnson Vision Care, Inc. (US) | 2007-06-27 | — | — | EP | disclosed |
| WO-2006039466-A1 | WETTABLE HYDROGELS COMPRISING REACTIVE, HYDROPHILIC, POLYMERIC INTERNAL WETTING AGENTS | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2006-04-13 | — | — | WO | disclosed |
| US-20060072069-A1 | Wettable hydrogels comprising reactive, hydrophilic, polymeric internal wetting agents | JOHNSON & JOHNSON VISION CARE, INC. | 2006-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170136450-A1 | POLYMER CONTAINING CARBOXYL GROUP, PREPARATION METHOD AND APPLICATION THEREOF, SUPPORTED CATALYST AND PREPARATION METHODS THEREOF AND PREPARATION METHODS OF PENEM ANTIBIOTIC INTERMEDIATE | PGM2, MGAM, MRPL21 | ALDH1A1 3195/4885HRH3 3226/4885FFAR1 4680/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.