Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL14656583 | 0.82 | CA5A (0.43) | CA5ACA5BALDH1A1L3MBTL1TSHR | |
| SCHEMBL19832 | 0.82 | — | — | |
| Fluoromethane SCHEMBL22462247 | 0.78 | — | — | |
| Fluoride SCHEMBL3074894 | 0.78 | — | — | |
| Methane SCHEMBL20422713 | 0.78 | — | — | |
| SCHEMBL2618543 | 0.76 | ALDH1A1 (0.35) | ALDH1A1L3MBTL1 | |
| Propane SCHEMBL3456380 | 0.76 | — | — | |
| Fluoride Ion SCHEMBL3074892 | 0.76 | — | — | |
| Sulfuric Acid SCHEMBL6233490 | 0.75 | CA5A (0.50) | CA5ACA5BALDH1A1L3MBTL1TSHR | |
| SCHEMBL14133213 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1317406-B2 | PROCESS FOR OBTAINING A PURIFIED HYDROFLUOROALKANE | SOLVAY (BE) | 2012-11-14 | — | — | EP | disclosed |
| US-7750195-B2 | Process for obtaining a purified hydrofluoroalkane | SOLVAY S.A. (BE) | 2010-07-06 | — | — | US | disclosed |
| US-20090099394-A1 | PROCESS FOR OBTAINING A PURIFIED HYDROFLUOROALKANE | SOLVAY S.A. (BE) | 2009-04-16 | — | — | US | disclosed |
| US-7468467-B2 | Process for obtaining a purified hydrofluoroalkane | SOLVAY S.A. (BE) | 2008-12-23 | — | — | US | disclosed |
| EP-1985601-A2 | Process for obtaining a purified hydrofluoroalkane | SOLVAY (Société Anonyme) (BE) | 2008-10-29 | — | — | EP | disclosed |
| EP-1317406-B1 | PROCESS FOR OBTAINING A PURIFIED HYDROFLUOROALKANE | SOLVAY (BE) | 2008-08-20 | — | — | EP | disclosed |
| US-20070112231-A1 | Process for obtaining a purified hydrofluoroalkane | SOLVAY S.A. (BE) | 2007-05-17 | — | — | US | disclosed |
| US-7179949-B2 | Process for obtaining a purified hydrofluoroalkane | SOLVAY (SOCIETE ANONYME) (BE) | 2007-02-20 | — | — | US | disclosed |
| US-20040030204-A1 | Process for obtaining a purified hydrofluoroalkane | SOLVAY (SOCIETE ANONYME) (BE) | 2004-02-12 | — | — | US | disclosed |
| EP-1317406-A1 | PROCESS FOR OBTAINING A PURIFIED HYDROFLUOROALKANE | SOLVAY (Société Anonyme) (BE) | 2003-06-11 | — | — | EP | disclosed |
| WO-2002012153-A1 | PROCESS FOR OBTAINING A PURIFIED HYDROFLUOROALKANE | Solvay (Société Anonyme) (BE) | 2002-02-14 | — | — | WO | disclosed |