Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 2/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA7 | P43166 | 2/20 | 0.35 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | NT5E | P21589 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27963455 | 0.85 | CA2 (0.39) | CA5ACA5BTSHRTDP1ALDH1A1 | |
| Trifluoromethanesulfonic Acid SCHEMBL336431 | 0.85 | ALDH1A1 (0.43) | CA5ACA5BTSHRTDP1ALDH1A1 | |
| SCHEMBL9050706 | 0.85 | TSHR (0.38) | CA5ACA5BTSHRTDP1ALDH1A1 | |
| Sulfuric Acid SCHEMBL4353784 | 0.82 | CA5A (0.60) | CA5ACA5BTSHRTDP1ALDH1A1 | |
| Sulfuric Acid SCHEMBL11313030 | 0.82 | CA5A (0.60) | CA5ACA5BTSHRTDP1ALDH1A1 | |
| Sulfuric Acid SCHEMBL9744014 | 0.82 | CA5A (0.60) | CA5ACA5BTSHRTDP1ALDH1A1 | |
| SCHEMBL575399 | 0.80 | — | — | |
| SCHEMBL1398392 | 0.80 | — | — | |
| SCHEMBL29156137 | 0.79 | TSHR (0.50) | TSHRTDP1ALDH1A1L3MBTL1CA2 | |
| SCHEMBL28449124 | 0.78 | CA1 (0.38) | TSHRTDP1CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112334497-A | Radiopaque polymers | 生物相容英国有限公司 | 2021-02-05 | — | — | CN | disclosed |
| CN-101698644-B | Method for efficiently preparing trifluroethyl vinyl ether without solvent | DONGYUE SHENZHOU NEW MAT CO | 2010-12-29 | — | — | CN | disclosed |
| CN-101698654-B | Method for preparing functional fluorine-containing monomers by bulk catalysis | DONGYUE SHENZHOU NEW MAT CO | 2010-11-10 | — | — | CN | disclosed |
| CN-101698654-A | Method for preparing functional fluorine-containing monomers by bulk catalysis | DONGYUE SHENZHOU NEW MAT CO | 2010-04-28 | — | — | CN | disclosed |
| CN-101698644-A | Method for efficiently preparing trifluroethyl vinyl ether without solvent | DONGYUE SHENZHOU NEW MAT CO | 2010-04-28 | — | — | CN | disclosed |
| CN-101698635-A | Preparation method of alkyl ether with ether terminal group | DONGYUE SHENZHOU NEW MAT CO | 2010-04-28 | — | — | CN | disclosed |
| US-20050010044-A1 | Polysaccharides and methods and intermediates useful for their preparation | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-01-13 | — | — | US | disclosed |
| WO-2005000907-A1 | SULFO-PROTECTED POLYSACCHARIDES AND METHODS AND INTERMEDIATES USEFUL FOR THEIR PREPARATION | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2005-01-06 | — | — | WO | disclosed |
| EP-0548616-A1 | Aqueous chemiluminescent systems | AMERICAN CYANAMID COMPANY (US) | 1993-06-30 | — | — | EP | disclosed |