SCHEMBL3674802

SCHEMBL3674802

C=CC(=O)SC(C)Sc1ccc(S(=O)(=O)c2ccc(SC(C)SC(=O)C=C)cc2)cc1

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
APEX1 P27695 2/20 0.35
KDM4E B2RXH2 2/20 0.35
MAPT P10636 4/20 0.33
ALDH1A1 P00352 4/20 0.33
PKM P14618 3/20 0.33
HPGD P15428 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
LMNA P02545 2/20 0.33
POLB P06746 1/20 0.33
HSD17B10 Q99714 1/20 0.33
TGM2 P21980 1/20 0.33
GAA P10253 2/20 0.32
ATM Q13315 1/20 0.31
ELANE P08246 1/20 0.31
DNMT1 P26358 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3674937 0.79 MAPT (0.37) APEX1KDM4EMAPTALDH1A1PKM
SCHEMBL3681041 0.78 GAA (0.36) KDM4EMAPTALDH1A1PKMHPGD
SCHEMBL14351325 0.75 APEX1 (0.41) APEX1KDM4EMAPTALDH1A1PKM
SCHEMBL3678272 0.70 PKM (0.36) KDM4EMAPTALDH1A1PKMHPGD
SCHEMBL3674803 0.68 CA2 (0.41) APEX1KDM4EMAPTALDH1A1LMNA
SCHEMBL10871424 0.67 LMNA (0.48) APEX1KDM4EMAPTALDH1A1PKM
SCHEMBL2240785 0.64 CYP2C19 (0.34) KDM4ESMN1; SMN2TGM2
SCHEMBL19594199 0.64 LMNA (0.54) KDM4EMAPTALDH1A1PKMSMN1; SMN2
SCHEMBL14351564 0.64 PKM (0.39) APEX1KDM4EMAPTALDH1A1PKM
SCHEMBL14351944 0.63 TSHR (0.41) APEX1KDM4EMAPTALDH1A1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8804245-B2 Stacked diffraction optical element including an optical element made of organic-inorganic composite resin material CANON KABUSHIKI KAISHA (JP) 2014-08-12 US disclosed
US-8344094-B2 Optical material and optical element CANON KABUSHIKI KAISHA (JP) 2013-01-01 US disclosed
US-20120200925-A1 ORGANIC-INORGANIC COMPOSITE RESIN COMPOSITION, ORGANIC-INORGANIC COMPOSITE RESIN MATERIAL, OPTICAL ELEMENT, AND STACKED DIFFRACTION OPTICAL ELEMENT CANON KABUSHIKI KAISHA (JP) 2012-08-09 US disclosed
EP-2484721-A1 Organic-inorganic composite resin composition, organic-inorganic composite resin material, optical element, and stacked diffraction optical element CANON KABUSHIKI KAISHA (JP) 2012-08-08 EP disclosed
US-20100076106-A1 OPTICAL MATERIAL AND OPTICAL ELEMENT CANON KABUSHIKI KAISHA (JP) 2010-03-25 US disclosed