Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | YAP1 | P46937 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylamine SCHEMBL28000459 | 0.80 | MAPT (0.44) | NPC1RAB9AALDH1A1KDM4EHDAC8 | |
| SCHEMBL12989766 | 0.80 | IRAK4 (0.41) | NPC1RAB9AL3MBTL1HPGDPOLB | |
| SCHEMBL3673483 | 0.79 | KMT5B (0.50) | NPC1RAB9AKDM4EHDAC8MAPT | |
| SCHEMBL18010743 | 0.79 | ALDH1A1 (0.49) | NPC1RAB9AL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL14051378 | 0.79 | MAPT (0.59) | NPC1RAB9AL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL3681747 | 0.79 | NPC1 (0.47) | NPC1RAB9AALDH1A1KDM4EHDAC8 | |
| SCHEMBL20384219 | 0.79 | ALDH1A1 (0.43) | RAB9AL3MBTL1ALDH1A1KDM4EHDAC8 | |
| SCHEMBL5608474 | 0.79 | HDAC8 (0.59) | L3MBTL1ALDH1A1KDM4EHDAC8MAPT | |
| SCHEMBL3679064 | 0.78 | MAPT (0.41) | ALDH1A1KDM4EHDAC8MAPTLMNA | |
| SCHEMBL16334269 | 0.77 | KMT5B (0.51) | NPC1RAB9AL3MBTL1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966225-B1 | TRANSITION METAL COMPLEXES AND PREPARATION METHODS THEREOF | LG CHEMICAL LTD (KR) | 2013-12-25 | — | — | EP | disclosed |
| EP-1966223-B1 | CATALYST COMPOSITION COMPRISING GROUP 4 TRANSITION METAL COMPLEXES AND METHOD FOR PREPARING POLYOLEFINS USING THE SAME | LG CHEMICAL LTD (KR) | 2013-08-14 | — | — | EP | disclosed |
| CN-102558245-A | Catalyst composition comprising group 4 transition metal complexes and method for preparing polyolefins using the same | LG CHEMICAL LTD | 2012-07-11 | — | — | CN | disclosed |
| US-7807762-B2 | Catalyst composition comprising Group 4 transition metal complexes and method for preparing polyolefins using the same | LG CHEM, LTD. (KR) | 2010-10-05 | — | — | US | disclosed |
| US-7678933-B2 | Transition metal complexes and preparation methods thereof | LG CHEM, LTD. (KR) | 2010-03-16 | — | — | US | disclosed |
| US-20090030221-A1 | Transition Metal Complexes and Preparation Methods Thereof | LG CHEM, LTD (KR) | 2009-01-29 | — | — | US | disclosed |
| US-20090005525-A1 | Catalyst Composition Comprising Group 4 Transition Metal Complexes and Method for Preparing Polyolefins Using the Same | LG CHEM , LTD. (KR) | 2009-01-01 | — | — | US | disclosed |
| CN-101300261-A | Catalyst composition comprising group 4 transition metal complexes and method for preparing polyolefins using the same | LG CHEMICAL LTD (KR) | 2008-11-05 | — | — | CN | disclosed |
| CN-101296932-A | Transition metal complex and preparation method thereof | LG CHEMICAL LTD (KR) | 2008-10-29 | — | — | CN | disclosed |
| EP-1966223-A1 | CATALYST COMPOSITION COMPRISING GROUP 4 TRANSITION METAL COMPLEXES AND METHOD FOR PREPARING POLYOLEFINS USING THE SAME | LG Chem. Ltd. (KR) | 2008-09-10 | — | — | EP | disclosed |
| EP-1966225-A1 | TRANSITION METAL COMPLEXES AND PREPARATION METHODS THEREOF | LG Chem, Ltd. (KR) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007078134-A1 | TRANSITION METAL COMPLEXES AND PREPARATION METHODS THEREOF | LG CHEM. LTD. (KR) | 2007-07-12 | — | — | WO | disclosed |
| WO-2007078133-A1 | CATALYST COMPOSITION COMPRISING GROUP 4 TRANSITION METAL COMPLEXES AND METHOD FOR PREPARING POLYOLEFINS USING THE SAME | LG CHEM. LTD. (KR) | 2007-07-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090030221-A1 | Transition Metal Complexes and Preparation Methods Thereof | PICALM, TEC, PPIP5K2 | NPC1 2837/4885RAB9A 2078/4885L3MBTL1 4576/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.