SCHEMBL3675708

SCHEMBL3675708

CC1(C)c2cc(-c3ccc(-c4ccccc4)cc3)c(-c3ccc(-c4ccccc4)cc3)cc2C(C)(C)c2cc(-c3ccc(-c4ccccc4)cc3)c(-c3ccc(-c4ccccc4)cc3)cc21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.41
BACE1 P56817 1/20 0.41
HPRT1 P00492 1/20 0.41
PTGS2 P35354 3/20 0.40
PGR P06401 1/20 0.40
LPL P06858 1/20 0.39
LIPG Q9Y5X9 1/20 0.39
HSD17B10 Q99714 2/20 0.39
TYRO3 Q06418 1/20 0.39
NTRK2 Q16620 1/20 0.39
CLK4 Q9HAZ1 1/20 0.39
DYRK1B Q9Y463 1/20 0.39
TDP2 O95551 1/20 0.38
MAPK1 P28482 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
TAAR1 Q96RJ0 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
MMP3 P08254 1/20 0.37
BCL2L1 Q07817 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12721335 0.82 ALDH1A1 (0.41) ALDH1A1BACE1PTGS2CYP1A2CYP3A4
SCHEMBL7141200 0.81 PDK2 (0.49) PGRHSD17B10TYRO3NTRK2CLK4
SCHEMBL12721328 0.77 PTGS2 (0.44) ALDH1A1PTGS2PGRLPLLIPG
SCHEMBL6825018 0.77 ALDH1A1 (0.60) ALDH1A1BACE1PTGS2HSD17B10MAPK1
SCHEMBL23263797 0.77 MEN1 (0.41) ALDH1A1PTGS2HSD17B10CYP3A4TAAR1
SCHEMBL22402010 0.77 PDK2 (0.36) ALDH1A1PGRHSD17B10CYP1A2CYP3A4
SCHEMBL21257313 0.77 MEN1 (0.41) ALDH1A1PTGS2HSD17B10CYP3A4TAAR1
SCHEMBL21257290 0.77 MEN1 (0.41) ALDH1A1PTGS2HSD17B10CYP3A4TAAR1
SCHEMBL21257144 0.77 MEN1 (0.41) ALDH1A1PTGS2HSD17B10CYP3A4TAAR1
SCHEMBL21028531 0.75 PDK2 (0.47) PGRTYRO3NTRK2CLK4DYRK1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7671241-B2 Host material for blue OLED and white light emitting device utilizing the same NATIONAL TSING HUA UNIVERSITY (TW) 2010-03-02 US disclosed
US-20090062570-A1 Host material for blue OLED and white light emitting device utilizing the same CHIEN-HONG CHENG 2009-03-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090062570-A1 Host material for blue OLED and white light emitting device utilizing the same OCIAD2, OCIAD1, CRY2 ALDH1A1 1517/4885BACE1 1967/4885HPRT1 471/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.