SCHEMBL3676576

SCHEMBL3676576

Cc1cccc(C(N)N)c1F

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.37
ESR1 P03372 1/20 0.37
SCN4A P35499 6/20 0.35
CYP1A2 P05177 4/20 0.35
CYP3A4 P08684 3/20 0.35
CYP2D6 P10635 3/20 0.35
NFKB1 P19838 3/20 0.35
MAOA P21397 2/20 0.35
LMNA P02545 2/20 0.35
SCN1A P35498 2/20 0.35
SCN5A Q14524 2/20 0.35
SCN9A Q15858 2/20 0.35
TSHR P16473 2/20 0.35
MAOB P27338 1/20 0.35
CYP2C9 P11712 1/20 0.35
KCNK3 O14649 1/20 0.35
CACNA1F O60840 1/20 0.35
KCNK2 O95069 1/20 0.35
GBA1 P04062 1/20 0.35
HTR2A P28223 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29945863 0.84 CYP1A2 (0.45) ACHEESR1SCN4ACYP1A2CYP3A4
SCHEMBL23520552 0.84 CYP1A2 (0.45) ACHEESR1SCN4ACYP1A2CYP3A4
SCHEMBL23526532 0.84 CYP1A2 (0.45) ACHEESR1SCN4ACYP1A2CYP3A4
SCHEMBL4547916 0.79 GABRA1 (0.46) ACHEESR1CYP1A2CYP3A4LMNA
SCHEMBL16951322 0.79 ACHE (0.39) ACHEESR1CYP1A2CYP3A4CYP2D6
SCHEMBL21608733 0.77 ACHE (0.37) ACHEESR1SCN4ACYP1A2CYP3A4
SCHEMBL3840264 0.76 ADRA2A (0.43) ACHEESR1SCN4ACYP1A2CYP3A4
SCHEMBL1642111 0.76 HTR2C (0.38) ACHEESR1CYP1A2CYP3A4LMNA
SCHEMBL16958041 0.76 ACHE (0.36) ACHEESR1SCN4ACYP1A2CYP3A4
SCHEMBL19682802 0.76 P2RX7 (0.43) ACHEESR1SCN4ACYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1426392-B1 COMPOSITION FOR OPTICAL MATERIAL MITSUBISHI GAS CHEMICAL CO (JP) 2010-02-24 EP disclosed
US-6960640-B2 Composition for optical material MITSUBISHI GAS CHEMICAL CO., LTD. (JP) 2005-11-01 US disclosed
US-20040147708-A1 Composition for optical material MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2004-07-29 US disclosed
EP-1426392-A1 COMPOSITION FOR OPTICAL MATERIAL MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2004-06-09 EP disclosed