Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 7/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL7200754 | 1.00 | ACHE (0.53) | ACHETDP1CYP3A4GAAALDH1A1 | |
| Bromide SCHEMBL7200758 | 1.00 | ACHE (0.53) | ACHETDP1CYP3A4GAAALDH1A1 | |
| SCHEMBL34181 | 0.97 | ACHE (0.57) | ACHETDP1CYP3A4GAAALDH1A1 | |
| SCHEMBL15661400 | 0.97 | ACHE (0.57) | ACHETDP1CYP3A4GAAALDH1A1 | |
| SCHEMBL5590712 | 0.93 | ACHE (0.53) | ACHETDP1CYP3A4GAAALDH1A1 | |
| SCHEMBL8849358 | 0.93 | ACHE (0.53) | ACHETDP1CYP3A4GAAALDH1A1 | |
| SCHEMBL5713304 | 0.93 | ACHE (0.53) | ACHETDP1CYP3A4GAAALDH1A1 | |
| SCHEMBL8773602 | 0.93 | ACHE (0.53) | ACHETDP1CYP3A4GAAALDH1A1 | |
| Hydrochloric Acid SCHEMBL14335453 | 0.93 | ACHE (0.53) | ACHETDP1CYP3A4GAAALDH1A1 | |
| Hydrochloric Acid SCHEMBL14335450 | 0.93 | ACHE (0.53) | ACHETDP1CYP3A4GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020132940-A1 | MACROMONOMERIC STABILIZER, PREPARATION METHOD THEREOF, AND METHOD FOR PREPARING POLYMERIC POLYOL | 万华化学集团股份有限公司 | 2020-07-02 | — | — | WO | claimed |
| EP-4696696-A1 | IMMOBILIZED QUATERNARY PHOSPHONIUM SALT HAVING PHENOL DOMAIN, METHOD FOR PRODUCING SAME, AND CYCLIC CARBONATE PRODUCTION METHOD USING SAME | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2026-02-18 | — | — | EP | disclosed |
| US-20250009883-A1 | METHOD | NATIONAL AND KAPODISTRIAN UNIVERSITY OF ATHENS (GR) | 2025-01-09 | — | — | US | disclosed |
| US-12121581-B2 | Method of photodynamic therapy | OSLO UNIVERSITETSSYKEHUS HF (NO) | 2024-10-22 | — | — | US | disclosed |
| WO-2024214491-A1 | IMMOBILIZED QUATERNARY PHOSPHONIUM SALT HAVING PHENOL DOMAIN, METHOD FOR PRODUCING SAME, AND CYCLIC CARBONATE PRODUCTION METHOD USING SAME | 信越化学工業株式会社 | 2024-10-17 | — | — | WO | disclosed |
| WO-2020132940-A1 | MACROMONOMERIC STABILIZER, PREPARATION METHOD THEREOF, AND METHOD FOR PREPARING POLYMERIC POLYOL | 万华化学集团股份有限公司 | 2020-07-02 | — | — | WO | disclosed |
| US-7678866-B2 | Polyethylene composition and process for producing same | TOSOH CORPORATION (JP) | 2010-03-16 | — | — | US | disclosed |
| EP-0881232-B1 | Catalyst for olefin polymerization and process for the production of an olefin polymer | TOSOH CORP (JP) | 2005-03-16 | — | — | EP | disclosed |
| EP-1473323-A1 | Polyethylene composition and process for producing same | Tosoh Corporation (JP) | 2004-11-03 | — | — | EP | disclosed |
| US-20040214953-A1 | Polyethylene composition and process for producing same | TOSOH CORPORATION | 2004-10-28 | — | — | US | disclosed |
| EP-0849288-B1 | Catalyst for polymerization of an olefin, and method for producing an olefin polymer | TOSOH CORP (JP) | 2002-11-27 | — | — | EP | disclosed |
| US-6034187-A | Catalyst for olefin polymerization and process for production of olefin polymer | TOSOH CORPORATION (JP) | 2000-03-07 | — | — | US | disclosed |
| US-5906955-A | Catalyst for polymerization of an olefin, and method for producing an olefin polymer | TOSOH CORPORATION (JP) | 1999-05-25 | — | — | US | disclosed |
| EP-0881232-A1 | Catalyst for olefin polymerization and process for production of olefin polymer | TOSOH CORPORATION (JP) | 1998-12-02 | — | — | EP | disclosed |
| EP-0849288-A1 | Catalyst for polymerization of an olefin, and method for producing an olefin polymer | TOSOH CORPORATION (JP) | 1998-06-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250009883-A1 | METHOD | MT-CO1, MT-ND2, PPIF | ACHE 4736/4885TDP1 936/4885CYP3A4 955/4885 |
| US-12121581-B2 | Method of photodynamic therapy | PPIF, MT-CO1, MT-ND2 | ACHE 4842/4885TDP1 1028/4885CYP3A4 680/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.