Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 4/20 | 0.59 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.59 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.59 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.59 |
| ▸ | DRD3 | P35462 | 1/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.59 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.59 |
| ▸ | PDK1 | Q15118 | 4/20 | 0.50 |
| ▸ | PDK2 | Q15119 | 4/20 | 0.50 |
| ▸ | PDK3 | Q15120 | 4/20 | 0.50 |
| ▸ | PDK4 | Q16654 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | AR | P10275 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22382729 | 0.75 | PGR (0.57) | PGRNR3C1SLC6A4NR1I2ADORA3 | |
| Norgestimate SCHEMBL38318 | 0.74 | PGR (1.00) | PGRNR3C1SLC6A4NR1I2ADORA3 | |
| Norgestimate SCHEMBL38317 | 0.74 | PGR (1.00) | PGRNR3C1SLC6A4NR1I2ADORA3 | |
| Norgestimate SCHEMBL633395 | 0.74 | PGR (1.00) | PGRNR3C1SLC6A4NR1I2ADORA3 | |
| Norgestimate SCHEMBL15233395 | 0.74 | PGR (1.00) | PGRNR3C1SLC6A4NR1I2ADORA3 | |
| Norgestimate SCHEMBL1411821 | 0.74 | PGR (1.00) | PGRNR3C1SLC6A4NR1I2ADORA3 | |
| Norgestimate SCHEMBL5523236 | 0.74 | PGR (1.00) | PGRNR3C1SLC6A4NR1I2ADORA3 | |
| Norgestimate SCHEMBL5173707 | 0.74 | PGR (1.00) | PGRNR3C1SLC6A4NR1I2ADORA3 | |
| SCHEMBL6462145 | 0.73 | PGR (0.49) | PGRNR3C1SLC6A4NR1I2ADORA3 | |
| Norgestimate SCHEMBL28685734 | 0.73 | PGR (0.98) | PGRNR3C1SLC6A4NR1I2ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003082336-A1 | FEMALE BIRTH CONTROL METHOD | JENCAP RESEARCH LTD. (CA) | 2003-10-09 | — | — | WO | claimed |
| US-20100063019-A1 | Low Dose Estrogen Interrupted Hormone Replacement Therapy | DURAMED PHARMACEUTICALS, INC. (US) | 2010-03-11 | — | — | US | disclosed |
| US-20080182828-A1 | Low Dose Estrogen Interrupted Hormone Replacement Therapy | DURAMED PHARMACEUTICALS, INC. (US) | 2008-07-31 | — | — | US | disclosed |
| US-7320970-B2 | Low dose estrogen interrupted hormone replacement therapy | DURAMED PHARMACEUTIALS, INC. (US) | 2008-01-22 | — | — | US | disclosed |
| US-20060211663-A1 | Low dose estrogen interrupted hormone replacement therapy | DURAMED PHARMACEUTICALS, INC. (US) | 2006-09-21 | — | — | US | disclosed |
| US-7078394-B2 | Low dose estrogen interrupted hormone replacement therapy | DURAMED PHARMACEUTICALS, INC. (US) | 2006-07-18 | — | — | US | disclosed |
| EP-1140109-B1 | TRIPHASIC ORAL CONTRACEPTIVE | ORTHO MCNEIL PHARM INC (US) | 2006-03-01 | — | — | EP | disclosed |
| US-20050038006-A1 | Triphasic oral contraceptive | SHANGOLD GARY A (US) | 2005-02-17 | — | — | US | disclosed |
| US-20040180867-A1 | Low dose estrogen interrupted hormone replacement therapy | DURAMED PHARMACEUTICALS, INC. | 2004-09-16 | — | — | US | disclosed |
| US-6747019-B2 | MIXTURE OF ESTROGEN, PROGESTERONE; ALTERNATING DOSAGE | JENCAP RESEARCH, LTD. (CA) | 2004-06-08 | — | — | US | disclosed |
| US-20020165209-A1 | Low dose estrogen interrupted hormone replacement therapy | JENCAP RESEARCH LTD. | 2002-11-07 | — | — | US | disclosed |
| EP-1165183-A1 | LOW DOSE ESTROGEN INTERRUPTED HORMONE REPLACEMENT THERAPY | JENCAP RESEARCH LIMITED (CA) | 2002-01-02 | — | — | EP | disclosed |
| US-20010044429-A1 | Triphasic oral contraceptive | SHANGOLD GARY A (US) | 2001-11-22 | — | — | US | disclosed |
| US-6214815-B1 | ETHINYLESTRADIOL AND NORGESTIMATE MIXTURES FOR CYCLES | ORTHO-MCNEIL PHARMACEUTICALS, INC. | 2001-04-10 | — | — | US | disclosed |
| WO-2000059577-A1 | LOW DOSE ESTROGEN INTERRUPTED HORMONE REPLACEMENT THERAPY | JENCAP RESEARCH LTD. (CA) | 2000-10-12 | — | — | WO | disclosed |