SCHEMBL3677579

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL197340	0.88	MGAM (0.48)	MGAMGAASIMGAM2TSHR
	SCHEMBL31364589	0.83	MGAM (0.39)	MGAMGAASIMGAM2TSHR
	SCHEMBL9468556	0.83	TSHR (0.54)	TSHRHSD17B10FAAHCES1CES2
	SCHEMBL9720470	0.83	PLOD2 (0.43)	HSD17B10FAAHCES1CES2MEN1
	SCHEMBL25223809	0.81	GAA (0.54)	MGAMGAASIMGAM2HSD17B10
	SCHEMBL3688748	0.81	CA14 (0.35)	HSD17B10FAAHCES1CES2MEN1
	SCHEMBL28100172	0.80	MGAM (0.65)	MGAMGAASIMGAM2TSHR
	SCHEMBL27976	0.80	MGAM (0.61)	MGAMGAASIMGAM2TSHR
	SCHEMBL6933557	0.79	MGAM (0.44)	MGAMGAASIMGAM2TSHR
	SCHEMBL15688315	0.77	MGAM (0.58)	MGAMGAASIMGAM2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.