Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16140056 | 0.75 | GRIA1 (0.41) | CYP1A2 | |
| SCHEMBL6584788 | 0.72 | CYP1A2 (0.46) | CYP1A2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL20282202 | 0.72 | NOS3 (0.39) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL7175506 | 0.70 | GRIN2D (0.41) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL29406232 | 0.70 | FYN (0.50) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL614525 | 0.70 | FYN (0.50) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL13072957 | 0.70 | FYN (0.38) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL3205225 | 0.69 | GRIN2D (0.50) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL7623499 | 0.69 | CYP1A2 (0.48) | CYP1A2CYP2A6CYP3A4CYP2C9 | |
| Hydrochloric Acid SCHEMBL866127 | 0.69 | FYN (0.48) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100068288-A1 | MIXTURES OR ORGANIC COMPOUNDS FOR THE TREATMENT OF AIRWAY DISEASES | CUENOUD BERNARD | 2010-03-18 | — | — | US | disclosed |
| US-7622484-B2 | Mixtures or organic compounds for the treatment of airway diseases | NOVARTIS AG (CH) | 2009-11-24 | — | — | US | disclosed |
| EP-1341542-B1 | Indanylderivatives for treating airway diseases | NOVARTIS AG (CH) | 2007-05-02 | — | — | EP | disclosed |
| US-20060052352-A1 | Mixtures or organic compounds for the treatment of airway diseases | NOVARTIS AG (CH) | 2006-03-09 | — | — | US | disclosed |
| US-7008951-B2 | Mixtures or organic compounds for the treatment of airway diseases | NOVARTIS AG (CH) | 2006-03-07 | — | — | US | disclosed |
| US-20050009795-A1 | Mixtures or organic compounds for the treatment of airway diseases | CUENOUD BERNARD (CH) | 2005-01-13 | — | — | US | disclosed |
| US-6800643-B2 | CORTICOSTEROID AND AN INDANYL-QUINOLINONE COMPOUND | NOVARTIS AG (CH) | 2004-10-05 | — | — | US | disclosed |
| US-20040038951-A1 | Organic compounds | NOVARTIS AG (CH) | 2004-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060052352-A1 | Mixtures or organic compounds for the treatment of airway diseases | NR3C2, CYP11B2, NR3C1 | CYP1A2 470/4885GRIN2D 3670/4885GRIN3B 2128/4885 |
| US-20040038951-A1 | Organic compounds | CYP11B2, NR3C2, CYP11B1 | CYP1A2 196/4885GRIN2D 3080/4885GRIN3B 1679/4885 |
| US-20100068288-A1 | MIXTURES OR ORGANIC COMPOUNDS FOR THE TREATMENT OF AIRWAY DISEASES | NR3C2, CYP11B2, NR3C1 | CYP1A2 470/4885GRIN2D 3670/4885GRIN3B 2128/4885 |
| US-20050009795-A1 | Mixtures or organic compounds for the treatment of airway diseases | NR3C2, CYP11B2, NR3C1 | CYP1A2 470/4885GRIN2D 3670/4885GRIN3B 2128/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.