Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 2/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.35 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 9/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 9/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 9/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 9/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 9/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3688899 | 0.72 | MEN1 (0.33) | GRIN1GRIN2A | |
| SCHEMBL16409282 | 0.71 | CHRM2 (0.47) | GRIN1GRIN2ALDHACHRM2CHRM4 | |
| SCHEMBL3688987 | 0.69 | HSD11B1 (0.35) | — | |
| SCHEMBL3686328 | 0.66 | TSHR (0.37) | — | |
| SCHEMBL1726760 | 0.66 | MAOA (0.31) | — | |
| SCHEMBL3691766 | 0.66 | CYP2D6 (0.32) | — | |
| SCHEMBL3679563 | 0.66 | LDHA (0.34) | LDHA | |
| SCHEMBL19308438 | 0.64 | CHRM2 (0.55) | GRIN1GRIN2ACHRM2CHRM4CHRM5 | |
| SCHEMBL1690206 | 0.64 | CHRM2 (0.55) | GRIN1GRIN2ACHRM2CHRM4CHRM5 | |
| SCHEMBL16409291 | 0.64 | CHRM2 (0.51) | GRIN1GRIN2ACHRM2CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3239137-B1 | (5R)-4,5-DIHYDRO-ISOXAZOLE DERIVATIVES AS WELL AS 1-(2-CHLOROACETYL)-4-PIPERIDINE-CARBONITRILE AND -CARBOXAMIDE DERIVATIVES AS INTERMEDIATES IN THE PREPARATION OF E.G. 4-[4-[(5R)-4,5-DIHYDRO-ISOXAZOL-3-YL]-THIAZOL-2-YL]-PIPERIDINE DERIVATIVES AS FUNGICIDES FOR CROP PROTECTION | DU PONT (US) | 2019-02-13 | — | — | EP | disclosed |
| EP-3239145-A1 | 1-[2-[3,5-SUBSTITUTED-1H-PYRAZOL-1-YL]ACETYL]-4-PIPERIDINE-CARBONITRILE AND -CARBOTHIAMIDE DERIVATIVES AS INTERMEDIATES IN THE PREPARATION OF FUNGICIDES FOR CROP PROTECTION | E. I. du Pont de Nemours and Company (US) | 2017-11-01 | — | — | EP | disclosed |
| EP-3239137-A1 | (5R)-4,5-DIHYDRO-ISOXAZOLE DERIVATIVES AS WELL AS 1-(2-CHLOROACETYL)-4-PIPERIDINE-CARBONITRILE AND -CARBOXAMIDE DERIVATIVES AS INTERMEDIATES IN THE PREPARATION OF E.G. 4-[4-[(5R)-4,5-DIHYDRO-ISOXAZOL-3-YL]-THIAZOL-2-YL]-PIPERIDINE DERIVATIVES AS FUNGICIDES FOR CROP PROTECTION | E. I. du Pont de Nemours and Company (US) | 2017-11-01 | — | — | EP | disclosed |
| EP-2049111-B1 | 1-(acetyl)-piperidine and 1-(acetyl)-piperazine derivatives as fungicides for use in plant protection | DU PONT (US) | 2017-05-24 | — | — | EP | disclosed |
| EP-2712616-B1 | Intermediates for the preparation of 1-(acetyl)-piperidine and 1-(acetyl)-piperazine derivatives as fungicides for use in plant protection | DU PONT (US) | 2017-04-19 | — | — | EP | disclosed |
| US-9604962-B2 | Fungicidal azocyclic amides | E I DU PONT DE NEMOURS AND COMPANY (US) | 2017-03-28 | — | — | US | disclosed |
| US-20150291556-A1 | FUNGICIDAL AZOCYCLIC AMIDES | CORTEVA AGRISCIENCE LLC | 2015-10-15 | — | — | US | disclosed |
| US-9090604-B2 | Fungicidal azocyclic amides | E I DU PONT DE NEMOURS AND COMPANY (US) | 2015-07-28 | — | — | US | disclosed |
| US-20140081027-A1 | FUNGICIDAL AZOCYCLIC AMIDES | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-03-20 | — | — | US | disclosed |
| US-8642634-B2 | Fungicidal azocyclic amides | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-02-04 | — | — | US | disclosed |
| US-8449898-B2 | Fungicidal mixtures | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-05-28 | — | — | US | disclosed |
| US-20100240619-A1 | FUNGICIDAL MIXTURES | CORTEVA AGRISCIENCE LLC | 2010-09-23 | — | — | US | disclosed |
| EP-2187748-A2 | FUNGICIDAL COMPOUNDS AND MIXTURES | E. I. du Pont de Nemours and Company (US) | 2010-05-26 | — | — | EP | disclosed |
| US-20090156592-A1 | Fungicidal Azocyclic Amides | E.I. DU PONT DE NEMOURS AND COMPANY (DE) | 2009-06-18 | — | — | US | disclosed |
| WO-2009055514-A2 | FUNGICIDAL MIXTURES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-04-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150291556-A1 | FUNGICIDAL AZOCYCLIC AMIDES | ARG1, NAT1, CHRM1 | GRIN1 228/4885GRIN2A 333/4885LDHA 4035/4885 |
| US-20140081027-A1 | FUNGICIDAL AZOCYCLIC AMIDES | ARG1, NAT1, CHRM1 | GRIN1 228/4885GRIN2A 333/4885LDHA 4035/4885 |
| US-20100240619-A1 | FUNGICIDAL MIXTURES | CYP1B1, CYP1A1, NOX1 | GRIN1 255/4885GRIN2A 1373/4885LDHA 4765/4885 |
| US-20090156592-A1 | Fungicidal Azocyclic Amides | ARG1, NAT1, CHRM1 | GRIN1 228/4885GRIN2A 333/4885LDHA 4035/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.