SCHEMBL367876

SCHEMBL367876

O=P(Oc1cccc2c1Cc1ccccc1O2)(Oc1cccc2c1Cc1ccccc1O2)Oc1cccc2c1Cc1ccccc1O2

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.48
MAOB P27338 1/20 0.48
MAPKAPK2 P49137 1/20 0.37
GAA P10253 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
ACSL1 P33121 1/20 0.33
DRD2 P14416 1/20 0.31
DRD1 P21728 1/20 0.31
DRD5 P21918 1/20 0.31
DRD3 P35462 1/20 0.31
NPC1 O15118 1/20 0.30
LMNA P02545 1/20 0.30
RAB9A P51151 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
SRC P12931 1/20 0.30
GPR84 Q9NQS5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL367878 0.88 MAOA (0.46) MAOAMAOBMAPKAPK2GAANPSR1
SCHEMBL7209204 0.87 MAOA (0.44) MAOAMAOBMAPKAPK2GAANPSR1
SCHEMBL6876165 0.82 MAOA (0.40) MAOAMAOBMAPKAPK2ACSL1SRC
SCHEMBL5344044 0.82 MAOA (0.57) MAOAMAOBMAPKAPK2GAANPSR1
SCHEMBL29934406 0.79 MAOA (0.53) MAOAMAOBMAPKAPK2DRD2DRD1
SCHEMBL5754978 0.79 MAOA (0.53) MAOAMAOBMAPKAPK2DRD2DRD1
SCHEMBL2715642 0.78 MAOA (0.48) MAOAMAOBMAPKAPK2GAANPSR1
SCHEMBL22205158 0.78 MAOA (0.48) MAOAMAOBMAPKAPK2GAANPSR1
SCHEMBL1581695 0.78 MAOA (0.48) MAOAMAOBMAPKAPK2GAANPSR1
SCHEMBL9274021 0.76 MAOA (0.50) MAOAMAOBMAPKAPK2GAANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3122326-A1 RAZOR COMPRISING A MOLDED SHAVING AID COMPOSITION COMPRISING A THERMALLY RESILIENT SENSATE The Gillette Company LLC (US) 2017-02-01 EP claimed
WO-2015148309-A1 RAZOR COMPRISING A MOLDED SHAVING AID COMPOSITION COMPRISING A THERMALLY RESILIENT SENSATE THE GILLETTE COMPANY (US) 2015-10-01 WO claimed
EP-1147765-B1 New active, compositions containing it and it's use in cosmetic, dermocosmetic, dermopharmacy or pharmacy, on woven or nonwoven fabrics SEPPIC SA (FR) 2006-05-03 EP claimed
US-7025955-B2 Method for maximizing scalp health and inducing enhanced visual and tactile hair quality SHAKLEE CORPORATION (US) 2006-04-11 US claimed
WO-2004010958-A2 A METHOD FOR MAXIMIZING SCALP HEALTH AND INDUCING ENHANCED VISUAL AND TACTILE HAIR QUALITY SHAKLEE CORPORATION (US) 2004-02-05 WO claimed
US-20030185784-A1 Novel active agent, composition containing it and use in the cosmetic, dermocosmetic, dermopharmaceutical or pharmaceutical field or on woven nonwoven supports SOCIETE D'EXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES SEPPIC (FR) 2003-10-02 US claimed
US-20020006906-A1 Novel active agent, composition containing it and use in the cosmetic, dermocosmetic, dermopharmaceutical or pharmaceutical field or on woven or nonwoven supports SOCIETE D'EXPLOITATION DE PRODUITS POUR LES 2002-01-17 US claimed
EP-1147765-A1 New active, compositions containing it and it's use in cosmetic, dermocosmetic, dermopharmacy or pharmacy, on woven or nonwoven fabrics SOCIETE D'EXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES, S.E.P.P.I.C. (FR) 2001-10-24 EP claimed
EP-4103287-A1 COMPOSITIONS COMPRISING (BIO)-ALKANEDIOLS AND COOLING AGENTS Symrise AG (DE) 2022-12-21 EP disclosed
WO-2022122903-A1 COMPOSITIONS COMPRISING (BIO)-ALKANEDIOLS AND COOLING AGENTS SYMRISE AG (DE) 2022-06-16 WO disclosed
US-20210069094-A1 HAIR CARE COMPOSITIONS MELALEUCA, INC. 2021-03-11 US disclosed
EP-3641724-A1 NOVEL SURFACTANT MIXTURE, NOVEL COMPOSITION COMPRISING SAME AND USE THEREOF IN COSMETICS Société d'Exploitation de Produits pour les Industries Chimiques SEPPIC (FR) 2020-04-29 EP disclosed
US-10334929-B2 Hair product application device The Pro-Motion Group, LLC (US) 2019-07-02 US disclosed
WO-2018234648-A1 NOVEL SURFACTANT MIXTURE, NOVEL COMPOSITION COMPRISING SAME AND USE THEREOF IN COSMETICS SOCIETE D'EXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES SEPPIC (FR) 2018-12-27 WO disclosed
WO-2002007707-A2 LINKAGE OF AGENTS USING MICROPARTICLES PERICOR SCIENCE, INC. (US) 2002-01-31 WO disclosed
US-20020006906-A1 Novel active agent, composition containing it and use in the cosmetic, dermocosmetic, dermopharmaceutical or pharmaceutical field or on woven or nonwoven supports SOCIETE D'EXPLOITATION DE PRODUITS POUR LES 2002-01-17 US disclosed
EP-1147765-A1 New active, compositions containing it and it's use in cosmetic, dermocosmetic, dermopharmacy or pharmacy, on woven or nonwoven fabrics SOCIETE D'EXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES, S.E.P.P.I.C. (FR) 2001-10-24 EP disclosed
WO-2001072262-A2 NEW COSMETIC, PERSONAL CARE, CLEANING AGENT, AND NUTRITIONAL SUPPLEMENT COMPOSITIONS COMPRISING BIOACTIVE GLASS AND METHODS OF MAKING AND USING THE SAME SCHOTT GLAS (DE) 2001-10-04 WO disclosed
WO-2001007009-A1 LYSINE OXIDASE LINKAGE OF AGENTS TO TISSUE PERICOR SCIENCE, INC. (US) 2001-02-01 WO disclosed
WO-2001006829-A2 LINKAGE OF AGENTS TO TISSUE PERICOR SCIENCE, INC. (US) 2001-02-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030185784-A1 Novel active agent, composition containing it and use in the cosmetic, dermocosmetic, dermopharmaceutical or pharmaceutical field or on woven nonwoven supports CUTA, PLOD3, SOST MAOA 1824/4885MAOB 2794/4885MAPKAPK2 2212/4885
US-20020006906-A1 Novel active agent, composition containing it and use in the cosmetic, dermocosmetic, dermopharmaceutical or pharmaceutical field or on woven or nonwoven supports CUTA, PLOD3, SOST MAOA 1972/4885MAOB 3006/4885MAPKAPK2 2406/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.