SCHEMBL367877

SCHEMBL367877

O=P(O)(O)OC1c2ccccc2Oc2ccccc21

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.48
MAOB P27338 1/20 0.48
ATM Q13315 2/20 0.46
HDAC3 O15379 1/20 0.43
HDAC4 P56524 1/20 0.43
HDAC1 Q13547 1/20 0.43
HDAC7 Q8WUI4 1/20 0.43
HDAC2 Q92769 1/20 0.43
HDAC10 Q969S8 1/20 0.43
HDAC11 Q96DB2 1/20 0.43
HDAC8 Q9BY41 1/20 0.43
HDAC6 Q9UBN7 1/20 0.43
HDAC9 Q9UKV0 1/20 0.43
HDAC5 Q9UQL6 1/20 0.43
CYP2C9 P11712 2/20 0.42
KCNA3 P22001 1/20 0.41
MAPT P10636 1/20 0.41
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
USP2 O75604 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28034476 0.98 MAOA (0.47) MAOAMAOBATMHDAC3HDAC4
SCHEMBL2345225 0.75 ACP3 (0.55) MAOAMAOBATMHDAC3HDAC4
SCHEMBL30876788 0.75 ACP3 (0.55) MAOAMAOBATMHDAC3HDAC4
SCHEMBL5344047 0.73 MAOA (0.56) MAOAMAOBATMHDAC3HDAC4
SCHEMBL29988174 0.73 MAOA (0.56) MAOAMAOBATMHDAC3HDAC4
SCHEMBL14015371 0.72 MAOA (0.50) MAOAMAOBATMHDAC3HDAC4
SCHEMBL5731331 0.72 ATM (0.52) MAOAMAOBATMHDAC3HDAC4
Water SCHEMBL10797327 0.71 MAOA (0.54) MAOAMAOBATMHDAC3HDAC4
SCHEMBL28929344 0.71 MAOA (0.54) MAOAMAOBATMHDAC3HDAC4
SCHEMBL7555796 0.70 ATM (0.50) MAOAMAOBATMHDAC3HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3122326-A1 RAZOR COMPRISING A MOLDED SHAVING AID COMPOSITION COMPRISING A THERMALLY RESILIENT SENSATE The Gillette Company LLC (US) 2017-02-01 EP claimed
WO-2015148309-A1 RAZOR COMPRISING A MOLDED SHAVING AID COMPOSITION COMPRISING A THERMALLY RESILIENT SENSATE THE GILLETTE COMPANY (US) 2015-10-01 WO claimed
EP-1147765-B1 New active, compositions containing it and it's use in cosmetic, dermocosmetic, dermopharmacy or pharmacy, on woven or nonwoven fabrics SEPPIC SA (FR) 2006-05-03 EP claimed
US-7025955-B2 Method for maximizing scalp health and inducing enhanced visual and tactile hair quality SHAKLEE CORPORATION (US) 2006-04-11 US claimed
WO-2004010958-A2 A METHOD FOR MAXIMIZING SCALP HEALTH AND INDUCING ENHANCED VISUAL AND TACTILE HAIR QUALITY SHAKLEE CORPORATION (US) 2004-02-05 WO claimed
US-20030185784-A1 Novel active agent, composition containing it and use in the cosmetic, dermocosmetic, dermopharmaceutical or pharmaceutical field or on woven nonwoven supports SOCIETE D'EXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES SEPPIC (FR) 2003-10-02 US claimed
US-20020006906-A1 Novel active agent, composition containing it and use in the cosmetic, dermocosmetic, dermopharmaceutical or pharmaceutical field or on woven or nonwoven supports SOCIETE D'EXPLOITATION DE PRODUITS POUR LES 2002-01-17 US claimed
EP-1147765-A1 New active, compositions containing it and it's use in cosmetic, dermocosmetic, dermopharmacy or pharmacy, on woven or nonwoven fabrics SOCIETE D'EXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES, S.E.P.P.I.C. (FR) 2001-10-24 EP claimed
EP-4103287-A1 COMPOSITIONS COMPRISING (BIO)-ALKANEDIOLS AND COOLING AGENTS Symrise AG (DE) 2022-12-21 EP disclosed
WO-2022122903-A1 COMPOSITIONS COMPRISING (BIO)-ALKANEDIOLS AND COOLING AGENTS SYMRISE AG (DE) 2022-06-16 WO disclosed
US-20210069094-A1 HAIR CARE COMPOSITIONS MELALEUCA, INC. 2021-03-11 US disclosed
EP-3641724-A1 NOVEL SURFACTANT MIXTURE, NOVEL COMPOSITION COMPRISING SAME AND USE THEREOF IN COSMETICS Société d'Exploitation de Produits pour les Industries Chimiques SEPPIC (FR) 2020-04-29 EP disclosed
US-10334929-B2 Hair product application device The Pro-Motion Group, LLC (US) 2019-07-02 US disclosed
WO-2018234648-A1 NOVEL SURFACTANT MIXTURE, NOVEL COMPOSITION COMPRISING SAME AND USE THEREOF IN COSMETICS SOCIETE D'EXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES SEPPIC (FR) 2018-12-27 WO disclosed
WO-2002007707-A2 LINKAGE OF AGENTS USING MICROPARTICLES PERICOR SCIENCE, INC. (US) 2002-01-31 WO disclosed
US-20020006906-A1 Novel active agent, composition containing it and use in the cosmetic, dermocosmetic, dermopharmaceutical or pharmaceutical field or on woven or nonwoven supports SOCIETE D'EXPLOITATION DE PRODUITS POUR LES 2002-01-17 US disclosed
EP-1147765-A1 New active, compositions containing it and it's use in cosmetic, dermocosmetic, dermopharmacy or pharmacy, on woven or nonwoven fabrics SOCIETE D'EXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES, S.E.P.P.I.C. (FR) 2001-10-24 EP disclosed
WO-2001072262-A2 NEW COSMETIC, PERSONAL CARE, CLEANING AGENT, AND NUTRITIONAL SUPPLEMENT COMPOSITIONS COMPRISING BIOACTIVE GLASS AND METHODS OF MAKING AND USING THE SAME SCHOTT GLAS (DE) 2001-10-04 WO disclosed
WO-2001007009-A1 LYSINE OXIDASE LINKAGE OF AGENTS TO TISSUE PERICOR SCIENCE, INC. (US) 2001-02-01 WO disclosed
WO-2001006829-A2 LINKAGE OF AGENTS TO TISSUE PERICOR SCIENCE, INC. (US) 2001-02-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030185784-A1 Novel active agent, composition containing it and use in the cosmetic, dermocosmetic, dermopharmaceutical or pharmaceutical field or on woven nonwoven supports CUTA, PLOD3, SOST MAOA 1824/4885MAOB 2794/4885ATM 3577/4885
US-20020006906-A1 Novel active agent, composition containing it and use in the cosmetic, dermocosmetic, dermopharmaceutical or pharmaceutical field or on woven or nonwoven supports CUTA, PLOD3, SOST MAOA 1972/4885MAOB 3006/4885ATM 3478/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.