Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16915056 | 0.82 | MEN1 (0.40) | MAPK1SMN1; SMN2MEN1KMT2ACYP2C19 | |
| SCHEMBL3679517 | 0.76 | CYP2C9 (0.35) | KCNA3MAPK1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL4470421 | 0.73 | HTT (0.38) | MEN1KMT2AATMCYP2C19CYP2C9 | |
| SCHEMBL31098894 | 0.70 | CYP19A1 (0.49) | MEN1KMT2ACYP3A4TSHRALDH1A1 | |
| SCHEMBL576440 | 0.69 | MMP2 (0.40) | MAPK1SMN1; SMN2MEN1KMT2ACYP2C9 | |
| SCHEMBL14350785 | 0.69 | MMP2 (0.40) | MAPK1SMN1; SMN2MEN1KMT2ACYP2C9 | |
| SCHEMBL30211173 | 0.69 | SMN1; SMN2 (0.42) | SMN1; SMN2MEN1KMT2ACYP2C19CYP3A4 | |
| SCHEMBL7488740 | 0.69 | OPRM1 (0.40) | — | |
| SCHEMBL577105 | 0.69 | MEN1 (0.41) | MAPK1SMN1; SMN2MEN1KMT2ACYP2C9 | |
| SCHEMBL28589027 | 0.68 | OPRM1 (0.50) | KCNA3MAPK1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7674741-B2 | Components and catalysts for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2010-03-09 | — | — | US | disclosed |
| EP-1756172-B1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE SRL (IT) | 2009-11-04 | — | — | EP | disclosed |
| CN-100519592-C | catalyst component and catalyst for olefin polymerization | BASELL POLIOLEFINE SRL (IT) | 2009-07-29 | — | — | CN | disclosed |
| US-20090118446-A1 | Components and catalysts for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2009-05-07 | — | — | US | disclosed |
| CN-1968974-A | Catalyst component and catalyst for olefin polymerization | BASELL POLIOLEFINE SRL (IT) | 2007-05-23 | — | — | CN | disclosed |
| EP-1756172-A2 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia S.r.l. (IT) | 2007-02-28 | — | — | EP | disclosed |
| WO-2005123784-A2 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2005-12-29 | — | — | WO | disclosed |