SCHEMBL576440

SCHEMBL576440

CC1(c2ccccc2)CCOC1=O

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 2/20 0.40
MMP9 P14780 2/20 0.40
MMP1 P03956 1/20 0.40
CCR2 P41597 1/20 0.39
MEN1 O00255 1/20 0.38
CYP2C9 P11712 1/20 0.38
KMT2A Q03164 1/20 0.38
HSD11B1 P28845 1/20 0.38
MAPK1 P28482 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
CHRM2 P08172 1/20 0.37
CHRM4 P08173 1/20 0.37
ALDH1A1 P00352 1/20 0.37
TSHR P16473 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14350785 1.00 MMP2 (0.40) MMP2MMP9MMP1CCR2MEN1
SCHEMBL576582 0.89 ALDH1A1 (0.39) MMP2MMP9MMP1CCR2MEN1
SCHEMBL577376 0.87 AKR1C1 (0.38) MMP2MMP9MMP1CCR2HSD11B1
SCHEMBL7034683 0.83 CCR2 (0.40) CCR2
SCHEMBL576540 0.80 BRD4 (0.41) MMP2MMP9MMP1CCR2MEN1
SCHEMBL7038682 0.80 SLC6A4 (0.44)
SCHEMBL5608693 0.79 ALDH1A1 (0.35) HSD11B1ALDH1A1TSHR
SCHEMBL7034677 0.78 POLB (0.40) HSD11B1ALDH1A1
SCHEMBL7035740 0.77 HCAR2 (0.44) KMT2AALDH1A1
SCHEMBL577105 0.76 MEN1 (0.41) MEN1CYP2C9KMT2AMAPK1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4904628-A Components and catalysts for the polymerization of olefins MONTEDISON S.P.A. (IT) 1990-02-27 US claimed
JP-6192316-A None JP disclosed
US-11616253-B2 Nonaqueous electrolyte for secondary battery and nonaqueous-electrolyte secondary battery employing the same MITSUBISHI CHEMICAL CORPORATION (JP) 2023-03-28 US disclosed
US-11367899-B2 Nonaqueous electrolyte for secondary battery and nonaqueous-electrolyte secondary battery employing the same MITSUBISHI CHEMICAL CORPORATION (JP) 2022-06-21 US disclosed
US-20210194058-A1 NONAQUEOUS ELECTROLYTE LIQUID BATTERY MAXELL HOLDINGS, LTD. (JP) 2021-06-24 US disclosed
CN-106848406-B Nonaqueous electrolyte solution for secondary battery and nonaqueous electrolyte secondary battery 三菱化学株式会社 2020-09-11 CN disclosed
CN-105633345-B Nonaqueous electrolyte solution for secondary battery and nonaqueous electrolyte secondary battery using same 三菱化学株式会社 2020-01-17 CN disclosed
US-10468720-B2 Nonaqueous electrolyte for secondary battery and nonaqueous-electrolyte secondary battery employing the same MITSUBISHI CHEMICAL CORPORATION (JP) 2019-11-05 US disclosed
US-20190288338-A1 NONAQUEOUS ELECTROLYTE FOR SECONDARY BATTERY AND NONAQUEOUS-ELECTROLYTE SECONDARY BATTERY EMPLOYING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2019-09-19 US disclosed
EP-2144321-B1 NONAQUEOUS ELECTROLYTE FOR SECONDARY BATTERY AND NONAQUEOUS ELECTROLYTE SECONDARY BATTERY EMPLOYING THE SAME MITSUBISHI CHEM CORP (JP) 2019-01-23 EP disclosed
US-20030225282-A1 Enantioselective process for preparing arylated lactones and derivatives ZHANG TONY YANTAO (US) 2003-12-04 US disclosed
EP-1286980-A2 ENANTIOSELECTIVE PROCESS FOR PREPARING ARYLATED LACTONES AND DERIVATIVES ELI LILLY AND COMPANY (US) 2003-03-05 EP disclosed
WO-2001072731-A2 ENANTIOSELECTIVE PROCESS FOR PREPARING ARYLATED LACTONES AND DERIVATIVES ELI LILLY AND COMPANY (US) 2001-10-04 WO disclosed
EP-0756590-A1 SYNTHESIS OF PROTOTYPES FOR RENIN INHIBITORS Novartis AG (CH) 1997-02-05 EP disclosed
WO-1995029150-A1 SYNTHESIS OF PROTOTYPES FOR RENIN INHIBITORS CIBA-GEIGY AG (CH) 1995-11-02 WO disclosed
JP-H06192316-A CATALYST FOR ALPHA-OLEFIN POLYMERIZATION MITSUI PETROCHEM IND LTD 1994-07-12 JP disclosed
US-4904628-A Components and catalysts for the polymerization of olefins MONTEDISON S.P.A. (IT) 1990-02-27 US disclosed
US-4585594-A CARBONYLATION OF ALLYL ALCOHOL DERIVATIVE BASF AKTIENGESELLSCHAFT (DE) 1986-04-29 US disclosed
US-4522930-A REACTION PRODUCT OF METALOORGANIC COMPOUND OF ALUMINUM, ELECTRON-DONOR COMPOUND REACTIVE WITH MAGNESIUM CHLORIDE AND A SOLID HALOGENATED TITANIUM COMPOUND MONTEDISON S.P.A. (IT) 1985-06-11 US disclosed
EP-0086473-A2 Components and catalysts for the polymerization of olefins Montedison S.p.A. (IT) 1983-08-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030225282-A1 Enantioselective process for preparing arylated lactones and derivatives CYP51A1, AHR, LSS MMP2 4334/4885MMP9 4560/4885MMP1 4817/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.