Medronic Acid

Medronic Acid

SCHEMBL367902

NCN.O=P(O)(O)CP(=O)(O)O.O=P(O)(O)CP(=O)(O)O.O=P(O)(O)CP(=O)(O)O.O=P(O)(O)CP(=O)(O)O

nearest known ligand 0.77

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.77
MMP2 P08253 1/20 0.77
THRB P10828 1/20 0.77
MAPK1 P28482 1/20 0.77
HSD17B10 Q99714 1/20 0.77
OTC P00480 1/20 0.61
ALDH1A1 P00352 1/20 0.50
LMNA P02545 2/20 0.45
BLM P54132 2/20 0.45
CYP3A4 P08684 1/20 0.45
NFKB1 P19838 1/20 0.45
PMP22 Q01453 1/20 0.45
ANPEP P15144 1/20 0.45
ERAP2 Q6P179 1/20 0.45
GABBR2 O75899 2/20 0.41
GABBR1 Q9UBS5 2/20 0.41
TYMS P04818 1/20 0.39
LAP3 P28838 1/20 0.36
FDPS P14324 1/20 0.36
GLUL P15104 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Medronic Acid SCHEMBL78977 0.89 KDM4E (0.71) KDM4EMMP2THRBMAPK1HSD17B10
Medronic Acid SCHEMBL9550946 0.89 KDM4E (0.71) KDM4EMMP2THRBMAPK1HSD17B10
Medronic Acid SCHEMBL1485658 0.89 KDM4E (0.71) KDM4EMMP2THRBMAPK1HSD17B10
Medronic Acid SCHEMBL2353950 0.89 KDM4E (0.71) KDM4EMMP2THRBMAPK1HSD17B10
Medronic Acid SCHEMBL19350137 0.89 KDM4E (0.71) KDM4EMMP2THRBMAPK1HSD17B10
Medronic Acid SCHEMBL12492957 0.89 KDM4E (0.71) KDM4EMMP2THRBMAPK1HSD17B10
Medronic Acid SCHEMBL7743864 0.89 KDM4E (0.71) KDM4EMMP2THRBMAPK1HSD17B10
Medronic Acid SCHEMBL1707898 0.89 KDM4E (0.71) KDM4EMMP2THRBMAPK1HSD17B10
Medronic Acid SCHEMBL2823010 0.89 KDM4E (0.71) KDM4EMMP2THRBMAPK1HSD17B10
Medronic Acid SCHEMBL241941 0.89 KDM4E (0.71) KDM4EMMP2THRBMAPK1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040220151-A1 Process for treating tissue and suppressing pain MINU, L.L.C. 2004-11-04 US claimed
EP-3437730-B1 METHOD FOR MANUFACTURING WATER ABSORBING AGENT NIPPON CATALYTIC CHEM IND (JP) 2024-04-17 EP disclosed
EP-3437732-B1 PARTICULATE WATER ABSORBING AGENT NIPPON CATALYTIC CHEM IND (JP) 2022-05-11 EP disclosed
US-11224857-B2 Method for manufacturing water absorbing agent NIPPON SHOKUBAI CO., LTD. (JP) 2022-01-18 US disclosed
US-10696895-B2 Acrylic acid crosslinked polymer and use thereof NIPPON SHOKUBAI CO., LTD. (JP) 2020-06-30 US disclosed
US-10562006-B2 Particulate water absorbing agent NIPPON SHOKUBAI CO., LTD. (JP) 2020-02-18 US disclosed
EP-2163302-B1 PARTICULATE WATER-ABSORBING AGENT AND METHOD FOR PRODUCING THE SAME NIPPON CATALYTIC CHEM IND (JP) 2019-07-03 EP disclosed
EP-3023369-B1 PROCESS FOR PRODUCTION OF WATER-ABSORBING RESINS NIPPON CATALYTIC CHEM IND (JP) 2019-06-26 EP disclosed
US-20190111411-A1 PARTICULATE WATER ABSORBING AGENT NIPPON SHOKUBAI CO., LTD. (JP) 2019-04-18 US disclosed
US-20190105633-A1 METHOD FOR MANUFACTURING WATER ABSORBING AGENT NIPPON SHOKUBAI CO., LTD. (JP) 2019-04-11 US disclosed
US-20090275470-A1 PARTICULATE WATER ABSORBING AGENT AND MANUFACTURING METHOD OF SAME NIPPON SHOKUBAI CO., LTD. (JP) 2009-11-05 US disclosed
EP-2057228-A1 PARTICULATE WATER ABSORBING AGENT AND PRODUCTION METHOD THEREOF Nippon Shokubai Co., Ltd. (JP) 2009-05-13 EP disclosed
WO-2008026772-A1 PARTICULATE WATER ABSORBING AGENT AND PRODUCTION METHOD THEREOF NIPPON SHOKUBAI CO., LTD. (JP) 2008-03-06 WO disclosed
US-7223416-B2 Topical composition MINU, L.L.C. (US) 2007-05-29 US disclosed
US-20060058378-A1 Reduced bioirritant composition MINU, L.L.C. 2006-03-16 US disclosed
US-20050187199-A1 applying a composition of an NSAID to a mucous membrane of a patient at risk for developing symptoms of Herpes simplex, Herpes zoster, or allergy; may also contain an anti-irritant such as a non-nutritive sweetener PEYMAN, GHOLAM A. 2005-08-25 US disclosed
US-20040220151-A1 Process for treating tissue and suppressing pain MINU, L.L.C. 2004-11-04 US disclosed
US-20040219110-A1 Process for removing calculus deposits from the teeth and suppressing pain MINU , L.L.C. 2004-11-04 US disclosed
US-4144324-A DIAMINEPHOSPHONATE COLGATE PALMOLIVE COMPANY (US) 1979-03-13 US disclosed
US-4143128-A A POLYMETHYLENEDIAMINE TETRA(METHYLENE PHOSPHONIC ACID) COLGATE PALMOLIVE COMPANY (US) 1979-03-06 US disclosed