SCHEMBL8355251

SCHEMBL8355251

COC(=O)C(F)(F)C(=O)CCl

nearest known ligand 0.33

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 1/20 0.33
CTRB1 P17538 1/20 0.33
ALDH1A1 P00352 2/20 0.32
DGAT1 O75907 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
MAPT P10636 1/20 0.32
GLA P06280 2/20 0.31
SRC P12931 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL197338 0.79 ALDH1A1 (0.33) KCNN4CTRB1ALDH1A1DGAT1MAPT
SCHEMBL4314333 0.79 ALDH1A1 (0.33) KCNN4CTRB1ALDH1A1DGAT1MEN1
SCHEMBL7914245 0.78 CYP4F2 (0.39) ALDH1A1MEN1KMT2AMAPTL3MBTL1
SCHEMBL2580230 0.77 DGAT1 (0.42) KCNN4CTRB1ALDH1A1DGAT1MEN1
SCHEMBL9569881 0.72 DGAT1 (0.39) KCNN4CTRB1ALDH1A1DGAT1MEN1
SCHEMBL17372996 0.71 ALDH1A1 (0.37) KCNN4CTRB1ALDH1A1DGAT1MEN1
SCHEMBL92058 0.70 DGAT1 (0.37) KCNN4ALDH1A1DGAT1MEN1KMT2A
SCHEMBL16115556 0.70 DGAT1 (0.37) KCNN4ALDH1A1DGAT1MAPTSRC
SCHEMBL8691775 0.70 TSHR (0.40) ALDH1A1L3MBTL1
SCHEMBL21393608 0.70 KCNN4 (0.38) KCNN4CTRB1ALDH1A1DGAT1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240410055-A1 METHOD AND FORMULATION FOR PREPARING OPTICAL METAL OXIDE LAYERS MERCK PATENT GMBH (DE) 2024-12-12 US disclosed
WO-2023057401-A1 METHOD AND FORMULATION FOR PREPARING OPTICAL METAL OXIDE LAYERS MERCK PATENT GMBH (DE) 2023-04-13 WO disclosed
US-5877119-A HERBICIDE ROHM AND HAAS COMPANY (US) 1999-03-02 US disclosed
US-5843867-A Substituted pyridine compounds ROHM AND HAAS COMPANY (US) 1998-12-01 US disclosed
US-5824625-A HERBICIDES, HETEROCYCLIC GROUP(S) ATTACHED TO PYRIDINE RING ROHM AND HAAS COMPANY 1998-10-20 US disclosed
US-5643854-A HERBICIDES ROHM AND HAAS COMPANY (US) 1997-07-01 US disclosed
US-5512536-A HERBICIDE ROHN AND HAAS COMPANY (US) 1996-04-30 US disclosed
US-5424274-A Herbicides ROHM AND HAAS COMPANY (US) 1995-06-13 US disclosed
US-5391540-A Herbicides ROHM AND HAAS COMPANY (US) 1995-02-21 US disclosed
EP-0435843-B1 Substituted pyridine compounds MONSANTO CO (US) 1994-06-15 EP disclosed
US-5219824-A Preemergence, postemergence herbicides MONSANTO COMPANY (US) 1993-06-15 US disclosed
EP-0278944-B1 SUBSTITUTED 2,6-SUBSTITUTED PYRIDINE COMPOUNDS Monsanto Company (US) 1992-09-30 EP disclosed
WO-1992014711-A1 SUBSTITUTED PYRIDINE COMPOUNDS MONSANTO COMPANY (US) 1992-09-03 WO disclosed
US-5129943-A Herbicides MONSANTO COMPANY (US) 1992-07-14 US disclosed
US-5125956-A Preemergence herbicides MONSANTO COMPANY (US) 1992-06-30 US disclosed
US-5100461-A Substituted 2,6-substituted pyridine compounds having herbicidal activity MONSANTO COMPANY (US) 1992-03-31 US disclosed
US-4988384-A HERBICIDES, PLANT GROWTH REGULATORS, ANTIGROWTH AGENTS MONSANTO COMPANY (US) 1991-01-29 US disclosed
US-4826532-A HERBICIDES MONSANTO COMPANY (US) 1989-05-02 US disclosed
EP-0278945-A2 Substituted 2,6-substituted pyridine compounds Monsanto Company (US) 1988-08-17 EP disclosed
EP-0278944-A1 Substituted 2,6-substituted pyridine compounds Monsanto Company (US) 1988-08-17 EP disclosed