Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | CES1 | P23141 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL367935 | 0.91 | CES2 (0.57) | CES2LMNACES1ALDH1A1KDM4E | |
| SCHEMBL10794852 | 0.86 | CES2 (0.68) | CES2LMNACES1ALDH1A1KDM4E | |
| SCHEMBL10794860 | 0.84 | LMNA (0.65) | CES2LMNACES1ALDH1A1KDM4E | |
| SCHEMBL6203480 | 0.82 | CES2 (0.61) | CES2LMNACES1ALDH1A1MAPK1 | |
| SCHEMBL8622979 | 0.78 | CES2 (0.56) | CES2LMNACES1ALDH1A1MAPK1 | |
| SCHEMBL71432 | 0.77 | AKR1C3 (0.61) | KDM4EAKR1C3NPC1RAB9ANR4A2 | |
| Benzoin SCHEMBL23361760 | 0.76 | LMNA (0.78) | CES2LMNACES1ALDH1A1KDM4E | |
| Benzoin SCHEMBL183095 | 0.76 | LMNA (0.78) | CES2LMNACES1ALDH1A1KDM4E | |
| SCHEMBL11605854 | 0.76 | CES2 (0.71) | CES2LMNACES1ALDH1A1KDM4E | |
| Water SCHEMBL27971095 | 0.76 | AKR1C3 (0.59) | KDM4EAKR1C3NPC1RAB9ANR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 751 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116256214-A | Method for purifying, separating and preparing saturated hydrocarbon mineral oil and aromatic hydrocarbon mineral oil on line | 北京市科学技术研究院分析测试研究所(北京市理化分析测试中心) | 2023-06-13 | — | — | CN | claimed |
| CN-115304659-A | Valactamide A and synthesis method of diastereoisomer | 北京大学深圳研究生院 | 2022-11-08 | — | — | CN | claimed |
| CN-106673988-B | Benzyl subunit cyclohexenone derivative and preparation method and medical application thereof | 南通大学 | 2020-04-10 | — | — | CN | claimed |
| US-20190002597-A1 | PROCESS FOR EPOXIDATION OF UNSATURATED POLYMER | ARLANXEO SINGAPORE PTE. LTD. (SG) | 2019-01-03 | — | — | US | claimed |
| CN-105646300-B | A kind of preparation method of the 2 pungent naphthoquinones of sulfoxide 1,4 | 黑龙江八农垦大学 | 2017-11-10 | — | — | CN | claimed |
| CN-104497086-A | Androstane-3beta, 5alpha, 6beta,19-tetraol as well as preparation method and application thereof | UNIV SUN YAT SEN | 2015-04-08 | — | — | CN | claimed |
| US-20240238305-A1 | FORMULATIONS OF 3-((3-(4-(2-(ISOBUTYLSULFONYL)PHENOXY)-3-(TRIFLUOROMETHYL)PHENYL)-1,2,4-OXADIAZOL-5-YL)METHYL)-5,5-DIMETHYL-1-(2-MORPHOLINOETHYL)IMIDAZOLIDINE-2,4-DIONE | NOVARTIS AG (CH) | 2024-07-18 | — | — | US | disclosed |
| EP-4005568-B1 | SGLTS/DPP4 INHIBITOR AND APPLICATION THEREOF | DONGBAO PURPLE STAR HANGZHOU BIOPHARMACEUTICAL CO LTD (CN) | 2024-07-10 | — | — | EP | disclosed |
| EP-4397664-A1 | PYRIMIDINE-FUSED CYCLIC COMPOUND AND PREPARATION METHOD AND USE THEREOF | Genfleet Therapeutics (Shanghai) Inc. (CN) | 2024-07-10 | — | — | EP | disclosed |
| EP-3712150-B1 | MACROCYCLIC COMPOUND SERVING AS WEE1 INHIBITOR AND APPLICATIONS THEREOF | WUXI BIOCITY BIOPHARMACEUTICS CO LTD (CN) | 2024-06-12 | — | — | EP | disclosed |
| EP-4353309-A1 | PHENYL UREA DERIVATIVE | Sumitomo Pharma Co., Ltd. (JP) | 2024-04-17 | — | — | EP | disclosed |
| EP-4349828-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Shanghai Yingli Pharmaceutical Co. Ltd. (CN) | 2024-04-10 | — | — | EP | disclosed |
| CN-117567379-A | Preparation method of 2- (1-piperazinyl) pyrimidine | 扬州市普林斯医药科技有限公司 | 2024-02-20 | — | — | CN | disclosed |
| CN-85108556-A | The preparation method of novel benzoxazol base and benzothiazolyl amino derivative and application thereof | — | 1986-07-30 | — | — | CN | disclosed |
| US-4569690-A | HERBICIDES, FUNGICIDES, PLANT DESSICANTS, DEFOLIANTS | UNIROYAL, INC. (US) | 1986-02-11 | — | — | US | disclosed |
| EP-0170105-A2 | Benzoic acid derivatives | Shudo, Koichi, Prof. Dr. (JP) | 1986-02-05 | — | — | EP | disclosed |
| EP-0110280-A1 | Process for the production of penem compounds | SCHERING CORPORATION (US) | 1984-06-13 | — | — | EP | disclosed |
| EP-0104940-A1 | 3-Aryl-5,6-dihydro-1,4,2-oxathiazines and their oxides | UNIROYAL, INC. (US) | 1984-04-04 | — | — | EP | disclosed |
| US-4397784-A | AMINO ACID DERIVATIVE ANTIBIOTICS | ABBOTT LABORATORIES (US) | 1983-08-09 | — | — | US | disclosed |
| US-4126573-A | DIPEROXYAZELAIC ACID OR DIPEROXYDODECANEDIOIC ACID PARTICLES COATED WITH A SURFACTANT | THE PROCTER & GAMBLE COMPANY (US) | 1978-11-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240238305-A1 | FORMULATIONS OF 3-((3-(4-(2-(ISOBUTYLSULFONYL)PHENOXY)-3-(TRIFLUOROMETHYL)PHENYL)-1,2,4-OXADIAZOL-5-YL)METHYL)-5,5-DIMETHYL-1-(2-MORPHOLINOETHYL)IMIDAZOLIDINE-2,4-DIONE | MGST1, MGAT3, DMPK | CES2 4878/4885LMNA 4283/4885CES1 3611/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.