Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | CES1 | P23141 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.49 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | PTGIR | P43119 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8622986 | 0.91 | CES2 (0.56) | CES2LMNACES1MAPK1ALOX15 | |
| SCHEMBL12114012 | 0.84 | CES2 (0.61) | CES2LMNACES1ALOX15PTPN7 | |
| SCHEMBL29367304 | 0.82 | LMNA (0.54) | CES2LMNACES1MAPK1ALOX15 | |
| SCHEMBL6203480 | 0.81 | CES2 (0.61) | CES2LMNACES1MAPK1ALDH1A1 | |
| SCHEMBL5775340 | 0.81 | NR4A2 (0.65) | NR4A2 | |
| SCHEMBL5315044 | 0.79 | ALOX15 (0.63) | LMNAMAPK1ALOX15PTPN7PKM | |
| SCHEMBL367936 | 0.78 | CES2 (0.57) | CES2LMNACES1MAPK1NR4A2 | |
| SCHEMBL10167730 | 0.78 | NR4A2 (0.65) | LMNAMAPK1ALOX15PTPN7PKM | |
| SCHEMBL18038294 | 0.76 | HTT (0.63) | LMNAMAPK1ALOX15PTPN7PKM | |
| SCHEMBL413254 | 0.76 | LMNA (0.81) | LMNAMAPK1ALOX15PTPN7PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5767288-A | DITHIANE-BENZOIN ADDUCTS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1998-06-16 | — | — | US | disclosed |