SCHEMBL3680169

SCHEMBL3680169

Cc1cc(-c2cccc3ccccc23)c(O)c(-c2cccc3ccccc23)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.45
MAOB P27338 1/20 0.45
CYP1A2 P05177 2/20 0.44
CYP2A6 P11509 2/20 0.44
ALDH1A1 P00352 2/20 0.43
PTGS1 P23219 1/20 0.42
PTGS2 P35354 1/20 0.42
MCL1 Q07820 1/20 0.41
ACMSD Q8TDX5 1/20 0.41
KDM4E B2RXH2 3/20 0.41
MAPT P10636 1/20 0.41
PTPN22 Q9Y2R2 1/20 0.41
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
HPGD P15428 1/20 0.41
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA9 Q16790 1/20 0.40
MEN1 O00255 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17500079 0.91 CYP1A2 (0.48) MAOAMAOBCYP1A2CYP2A6ALDH1A1
SCHEMBL13044875 0.88 F2 (0.42) MAOAMAOBCYP1A2CYP2A6ALDH1A1
SCHEMBL5129072 0.87 CYP3A4 (0.43) MAOAMAOBCYP1A2CYP2A6ALDH1A1
SCHEMBL17500089 0.85 SMN1; SMN2 (0.50) MAOAMAOBCYP1A2CYP2A6ALDH1A1
SCHEMBL13508862 0.85 HTR7 (0.38) MAOAMAOBALDH1A1PTGS1PTGS2
SCHEMBL7951078 0.84 CYP1A2 (0.57) MAOAMAOBCYP1A2CYP2A6ALDH1A1
SCHEMBL13043993 0.84 HTR1B (0.46) ALDH1A1MCL1KDM4EHPGDMEN1
SCHEMBL30336104 0.83 CYP1A2 (0.54) CYP1A2CYP2A6ALDH1A1MCL1ACMSD
SCHEMBL599137 0.83 CYP1A2 (0.54) CYP1A2CYP2A6ALDH1A1MCL1ACMSD
SCHEMBL13508864 0.83 TDP1 (0.37) MAOAMAOBALDH1A1PTGS1PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1910427-B1 ARYLPHENOXY CATALYST SYSTEM FOR PRODUCING ETHYLENE HOMOPOLYMER OR COPOLYMERS OF ETHYLENE AND ALPHA-OLEFINS SK INNOVATION CO LTD (KR) 2015-05-13 EP disclosed
US-7833926-B2 Arylphenoxy catalyst system for producing ethylene homopolymer or copolymers of ethylene and α-olefins SK ENERGY CO., LTD. (KR) 2010-11-16 US disclosed
US-20090326175-A1 ARYLPHENOXY CATALYST SYSTEM FOR PRODUCING ETHYLENE HOMOPOLYMER OR COPOLYMERS OF ETHYLENE AND a-OLEFINS SK ENERGY CO., LTD. (KR) 2009-12-31 US disclosed
US-7589042-B2 Arylphenoxy catalyst system for producing ethylene homopolymer or copolymers of ethylene and α-olefins SK CORPORATION (KR) 2009-09-15 US disclosed
EP-1910427-A1 ARYLPHENOXY CATALYST SYSTEM FOR PRODUCING ETHYLENE HOMOPOLYMER OR COPOLYMERS OF ETHYLENE AND ALPHA-OLEFINS SK Energy Co., Ltd. (KR) 2008-04-16 EP disclosed
US-20070135297-A1 ARYLPHENOXY CATALYST SYSTEM FOR PRODUCING ETHYLENE HOMOPOLYMER OR COPOLYMERS OF ETHYLENE AND a-OLEFINS SK CORPORATION (KR) 2007-06-14 US disclosed
WO-2007040294-A1 ARYLPHENOXY CATALYST SYSTEM FOR PRODUCING ETHYLENE HOMOPOLYMER OR COPOLYMERS OF ETHYLENE AND ALPHA-OLEFINS SK ENERGY CO., LTD. (KR) 2007-04-12 WO disclosed
US-20070004586-A1 Arylphenoxy catalyst system for producing ethylene homopolymer or copolymers of ethylene and alpha-olefins SK CORPORATION (KR) 2007-01-04 US disclosed
EP-0054942-B1 ADHESIVES FOR BONDING OPTICAL ELEMENTS MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1986-03-05 EP disclosed
EP-0054942-A1 Adhesives for bonding optical elements MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1982-06-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090326175-A1 ARYLPHENOXY CATALYST SYSTEM FOR PRODUCING ETHYLENE HOMOPOLYMER OR COPOLYMERS OF ETHYLENE AND a-OLEFINS ESR1, ERO1A, PPOX MAOA 901/4885MAOB 696/4885CYP1A2 235/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.