SCHEMBL3680273

SCHEMBL3680273

CCCC(C)O[Si](OCC)(OCC)N1C(=O)C=CC1=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3674531 0.82 FOS (0.30)
SCHEMBL3679923 0.79 MGLL (0.41)
SCHEMBL11522607 0.66
SCHEMBL3662154 0.64
SCHEMBL669765 0.64
SCHEMBL27658654 0.63
SCHEMBL27783311 0.63 OPRM1 (0.30)
Ammonia Solution, Strong SCHEMBL28104111 0.63
SCHEMBL1703986 0.62 MGLL (0.42)
SCHEMBL5552640 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8597790-B2 Rubber compositions containing non-sulfur silica coupling agents bound to diene rubbers BRIDGESTONE CORPORATION (JP) 2013-12-03 US disclosed
US-20130274374-A1 RUBBER COMPOSITIONS CONTAINING NON-SULFUR SILICA COUPLING AGENTS BOUND TO DIENE RUBBERS BRIDGESTONE CORPORATION (JP) 2013-10-17 US disclosed
US-8329297-B2 Rubber compositions containing non-sulfur silica coupling agents bound to diene rubbers BRIDGESTONE CORPORATION (JP) 2012-12-11 US disclosed
US-20100132868-A1 RUBBER COMPOSITIONS CONTAINING NON-SULFUR SILICA COUPLING AGENTS BOUND TO DIENE RUBBERS BRIDGESTONE CORPORATION (JP) 2010-06-03 US disclosed
US-7238740-B2 Rubber composition for a tire comprising a citraconimido-alkoxysilane as coupling agent MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) 2007-07-03 US disclosed
EP-1320569-B1 RUBBER COMPOSITION FOR TYRE COMPRISING A CITRACONIMIDO-ALKOXYSILANE AS COUPLING AGENT MICHELIN SOC TECH (FR) 2007-04-18 EP disclosed
US-20030181562-A1 Rubber composition for a tire comprising a citraconimido-alkoxysilane as coupling agent COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2003-09-25 US disclosed
EP-1320569-A1 RUBBER COMPOSITION FOR TYRE COMPRISING A CITRACONIMIDO-ALKOXYSILANE AS COUPLING AGENT Société de Technologie Michelin (FR) 2003-06-25 EP disclosed
WO-2002022728-A1 RUBBER COMPOSITION FOR TYRE COMPRISING A CITRACONIMIDO-ALKOXYSILANE AS COUPLING AGENT SOCIETE DE TECHNOLOGIE MICHELIN (FR) 2002-03-21 WO disclosed