SCHEMBL3680658

SCHEMBL3680658

ClN(Cl)c1ccccc1Cc1ccccc1N(Cl)Cl

nearest known ligand 0.40

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HSPA5 P11021 1/20 0.40
PTPN1 P18031 2/20 0.36
PNMT P11086 1/20 0.32
IDO1 P14902 1/20 0.32
AR P10275 2/20 0.32
TAAR1 Q96RJ0 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10432946 0.80 APOBEC3G (0.43) HSPA5PTPN1
SCHEMBL8119882 0.80 MGLL (0.42) TAAR1
SCHEMBL7872085 0.76 TSHR (0.35)
Nitrogen SCHEMBL11690299 0.75 PTPN1 (0.46) PTPN1
Sulfuric Acid SCHEMBL11686511 0.74 PTPN1 (0.48) PTPN1
SCHEMBL29408555 0.74 AR (0.50) HSPA5ARTAAR1
SCHEMBL3871304 0.74 AR (0.50) HSPA5ARTAAR1
SCHEMBL2213135 0.74 HSPA5 (0.40) HSPA5PTPN1ARTAAR1
SCHEMBL11062027 0.70 ALDH1A1 (0.39) HSPA5PTPN1AR
SCHEMBL1241839 0.70 AR (0.53) HSPA5PTPN1AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8845886-B2 Functionalized filters for heavy oil upgrading EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2014-09-30 US claimed
US-20120298558-A1 FUNCTIONALIZED FILTERS FOR HEAVY OIL UPGRADING EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2012-11-29 US claimed
WO-2012162046-A2 FUNCTIONALIZED FILTERS FOR HEAVY OIL UPGRADING EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2012-11-29 WO claimed
US-7011694-B1 CO2-selective membranes containing amino groups UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 2006-03-14 US claimed
US-5756643-A EXHIBITS HIGH SELECTIVITY FOR SEPARATION OF AN AROMATIC/SATURATE MIXTURE EXXON RESEARCH AND ENGINEERING COMPANY (US) 1998-05-26 US claimed
US-5670052-A CROSSLINKED MEMBRANE EXXON RESEARCH & ENGINEERING COMPANY (US) 1997-09-23 US claimed
EP-0583958-B1 Polyimide/aliphatic polyester copolymers EXXON RESEARCH ENGINEERING CO (US) 1996-10-02 EP claimed
US-5550199-A MEMBRANES EXXON RESEARCH AND ENGINEERING COMPANY (US) 1996-08-27 US claimed
EP-0424041-B1 Membranes obtained from copolymers of polyimides and aliphatic polyesters. EXXON RESEARCH ENGINEERING CO (US) 1996-03-20 EP claimed
US-5093003-A Separation of aromatic from saturated hydrocarbons by semipermeable membrane EXXON RESEARCH AND ENGINEERING COMPANY (US) 1992-03-03 US claimed
US-5028685-A Polyesterurethanes, hard and soft segments, membranes for separation of aromatics from saturates EXXON RESEARCH & ENGINEERING COMPANY (US) 1991-07-02 US claimed
US-4990275-A Separation membrane EXXON RESEARCH AND ENGINEERING COMPANY (US) 1991-02-05 US claimed
US-4944880-A FOR SEPARATION OF AROMATIC AND NON-AROMATIC HYDROCARBONS EXXON RESEARCH AND ENGINEERING COMPANY (US) 1990-07-31 US claimed
US-8845886-B2 Functionalized filters for heavy oil upgrading EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2014-09-30 US disclosed
WO-2012162046-A2 FUNCTIONALIZED FILTERS FOR HEAVY OIL UPGRADING EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2012-11-29 WO disclosed
US-20120298558-A1 FUNCTIONALIZED FILTERS FOR HEAVY OIL UPGRADING EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2012-11-29 US disclosed
US-5093003-A Separation of aromatic from saturated hydrocarbons by semipermeable membrane EXXON RESEARCH AND ENGINEERING COMPANY (US) 1992-03-03 US disclosed
US-5028685-A Polyesterurethanes, hard and soft segments, membranes for separation of aromatics from saturates EXXON RESEARCH & ENGINEERING COMPANY (US) 1991-07-02 US disclosed
EP-0153628-A1 Process for producing polyurethane compositions having low hysteresis AIR PRODUCTS AND CHEMICALS, INC. (US) 1985-09-04 EP disclosed
US-4507459-A AROMATIC DIAMINE CHAIN EXTENDER, TIRES AIR PRODUCTS AND CHEMICALS, INC. (US) 1985-03-26 US disclosed