Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3683707 | 0.64 | ESR1 (0.32) | ESR1ESR2 | |
| SCHEMBL3683709 | 0.64 | ESR1 (0.32) | ESR1ESR2 | |
| SCHEMBL3680706 | 0.56 | ALDH1A1 (0.31) | — | |
| SCHEMBL3680704 | 0.56 | ALDH1A1 (0.31) | — | |
| SCHEMBL833139 | 0.55 | ESR1 (0.56) | ESR1ESR2 | |
| SCHEMBL198609 | 0.54 | TTR (0.52) | ESR1ESR2 | |
| SCHEMBL7228077 | 0.54 | MMP3 (0.57) | ESR1ESR2 | |
| SCHEMBL24365262 | 0.52 | NOS3 (0.39) | ESR1ESR2 | |
| SCHEMBL16211776 | 0.49 | KDM4E (0.37) | — | |
| SCHEMBL8432063 | 0.48 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2176209-A1 | NOVEL ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2010-04-21 | — | — | EP | disclosed |
| WO-2009012954-A1 | NOVEL ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2009-01-29 | — | — | WO | disclosed |