Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.52 |
| ▸ | ALB | P02768 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | EGLN2 | Q96KS0 | 3/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | P4HB | P07237 | 2/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12594013 | 0.84 | TTR (0.48) | TTRALBMEN1KMT2AESR1 | |
| SCHEMBL1312296 | 0.84 | TTR (0.72) | TTRALBMEN1KMT2AESR1 | |
| SCHEMBL3009450 | 0.84 | TTR (0.43) | TTRALBMEN1KMT2AESR1 | |
| SCHEMBL8773853 | 0.84 | TTR (0.72) | TTRALBMEN1KMT2AESR1 | |
| SCHEMBL411743 | 0.80 | ERN1 (0.58) | — | |
| SCHEMBL10493540 | 0.80 | NFKB1 (0.45) | TTRALBMEN1KMT2AAR | |
| SCHEMBL18398312 | 0.80 | TTR (0.44) | TTRALBMEN1KMT2AESR1 | |
| SCHEMBL18002603 | 0.78 | TTR (0.41) | TTRALBMEN1KMT2AESR1 | |
| SCHEMBL7228077 | 0.78 | MMP3 (0.57) | ESR1ESR2CA12CA2CA3 | |
| SCHEMBL157603 | 0.78 | CES2 (0.42) | TTRALBMEN1KMT2ATRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11773067-B2 | (Trifluoromethyl)pyrimidine-2-amine compounds | ELI LILLY AND COMPANY (US) | 2023-10-03 | — | — | US | claimed |
| CN-122036560-A | Radioactive medical isotope18F-labeled norepinephrine analogue as well as preparation method and application thereof | 中国医学科学院阜外医院 | 2026-05-15 | — | — | CN | disclosed |
| US-12617762-B2 | Carboxy derivatives with antiinflamatory properties | SITRYX THERAPEUTICS LIMITED (GB) | 2026-05-05 | — | — | US | disclosed |
| EP-4081511-B3 | CARBOXY DERIVATIVES WITH ANTIINFLAMMATORY PROPERTIES | SITRYX THERAPEUTICS LTD (GB) | 2026-03-04 | — | — | EP | disclosed |
| WO-2025224512-A1 | NOVEL COMPOUND AS 17-BETA-HYDROXYSTEROID DEHYDROGENASE 13 (HSD17B13) INHIBITOR AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 삼진제약주식회사 | 2025-10-30 | — | — | WO | disclosed |
| US-20250270162-A1 | KETONE INHIBITORS OF LYSINE GINGIPAIN | LIGHTHOUSE PHARMACEUTICALS, INC. (US) | 2025-08-28 | — | — | US | disclosed |
| US-12297322-B2 | Triazine-based membranes for gas separation | UT-BATTELLE, LLC (US) | 2025-05-13 | — | — | US | disclosed |
| US-20250129021-A1 | SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS | Interdict Bio, Inc. (US) | 2025-04-24 | — | — | US | disclosed |
| WO-2025064718-A1 | SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS | Interdict Bio, Inc. (US) | 2025-03-27 | — | — | WO | disclosed |
| US-20250092009-A1 | SUBSTITUTED CONDENSED THIOPHENES AS MODULATORS OF STING | CTXT PTY LTD (AU) | 2025-03-20 | — | — | US | disclosed |
| EP-0734363-B1 | FLUORINATION PROCESS | F2 CHEMICALS LIMITED (GB) | 1999-07-21 | — | — | EP | disclosed |
| US-5900502-A | Fluorination process | BNFL FLUOROCHEMICALS LIMITED (GB) | 1999-05-04 | — | — | US | disclosed |
| US-5643929-A | TREATMENT OF PICORNAVIRAL OR RHINOVIRUS AND CHEMICAL INTERMEDIATES | SANOFI WINTHROP, INC. (US) | 1997-07-01 | — | — | US | disclosed |
| EP-0734363-A1 | FLUORINATION PROCESS | BNFL FLUOROCHEMICALS LTD. (GB) | 1996-10-02 | — | — | EP | disclosed |
| EP-0512352-B1 | Substituted carboxylic acid derivatives | HOFFMANN LA ROCHE (CH) | 1996-03-27 | — | — | EP | disclosed |
| WO-1995016649-A1 | FLUORINATION PROCESS | BNFL FLUOROCHEMICALS LTD. (GB) | 1995-06-22 | — | — | WO | disclosed |
| US-5349068-A | 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents | STERLING WINTHROP INC. (US) | 1994-09-20 | — | — | US | disclosed |
| US-5344843-A | Carnitine acryltransferase enzyme inhibitors as antiischemic agents and for cardiovascular disorders | HOFFMAN-LA ROCHE INC. (US) | 1994-09-06 | — | — | US | disclosed |
| EP-0512352-A2 | Substituted carboxylic acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1992-11-11 | — | — | EP | disclosed |
| EP-0219143-A1 | Synergistic herbicidal compositions and methods of use | STAUFFER CHEMICAL COMPANY (US) | 1987-04-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11773067-B2 | (Trifluoromethyl)pyrimidine-2-amine compounds | P2RX1, P2RX2, P2RY1 | TTR 3174/4885ALB 3601/4885MEN1 3618/4885 |
| US-20250129021-A1 | SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS | MYC, KRAS, NRAS | TTR 1278/4885ALB 1014/4885MEN1 798/4885 |
| US-20250270162-A1 | KETONE INHIBITORS OF LYSINE GINGIPAIN | PHYKPL, ENPEP, PREP | TTR 3604/4885ALB 4774/4885MEN1 1912/4885 |
| US-12617762-B2 | Carboxy derivatives with antiinflamatory properties | CCR1, CBR1, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | TTR 3962/4885ALB 2545/4885MEN1 4588/4885 |
| US-20250092009-A1 | SUBSTITUTED CONDENSED THIOPHENES AS MODULATORS OF STING | STING1, CGAS, IRF3 | TTR 4170/4885ALB 3584/4885MEN1 1930/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.