SCHEMBL3682243

SCHEMBL3682243

C=C(CCc1ccc(C(=O)O)cc1)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.48
RARB P10826 6/20 0.47
TP53 P04637 1/20 0.46
TSHR P16473 1/20 0.46
KMT2A Q03164 3/20 0.45
MEN1 O00255 2/20 0.45
MAPT P10636 2/20 0.45
RARA P10276 1/20 0.45
MTOR P42345 1/20 0.45
FFAR1 O14842 1/20 0.42
SELL P14151 1/20 0.42
SELP P16109 1/20 0.42
SELE P16581 1/20 0.42
PPARA Q07869 1/20 0.41
SRD5A2 P31213 1/20 0.41
KEAP1 Q14145 1/20 0.41
KDM4E B2RXH2 1/20 0.41
USP2 O75604 1/20 0.41
POLB P06746 1/20 0.41
GAA P10253 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17940826 0.84 SRD5A2 (0.54) ALDH1A1KMT2AMEN1MAPTFFAR1
SCHEMBL7634724 0.82 FFAR1 (0.44) ALDH1A1TSHRFFAR1PPARAKEAP1
SCHEMBL17940817 0.82 FFAR1 (0.64) ALDH1A1MAPTFFAR1KEAP1SMN1; SMN2
SCHEMBL1137129 0.82 ESR1 (0.50) ALDH1A1TP53TSHRKMT2AMEN1
SCHEMBL30529 0.82 KEAP1 (0.61) ALDH1A1KMT2AMAPTFFAR1KEAP1
SCHEMBL4824446 0.81 FFAR1 (0.54) ALDH1A1FFAR1KDM4EGAA
SCHEMBL1921168 0.81 L3MBTL1 (0.51) ALDH1A1FFAR1KEAP1KDM4EPOLB
SCHEMBL2000488 0.81 RARB (0.56) ALDH1A1RARBTP53TSHRKMT2A
SCHEMBL1920376 0.81 FFAR1 (0.50) KMT2AMEN1FFAR1POLB
SCHEMBL1920945 0.81 FFAR1 (0.50) KMT2AMEN1MAPTFFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9890304-B2 Liquid optical adhesive compositions 3M INNOVATIVE PROPERTIES (US) 2018-02-13 US disclosed
US-9463146-B2 Addition-fragmentation oligomers 3M INNOVATIVE PROPERTIES COMPANY (US) 2016-10-11 US disclosed
US-9403966-B2 Addition-fragmentation agents 3M INNOVATIVE PROPERTIES COMPANY (US) 2016-08-02 US disclosed
US-9309443-B2 Liquid optical adhesive compositions 3M INNOVATIVE PROPERTIES COMPANY (US) 2016-04-12 US disclosed
US-20150328086-A1 ADDITION-FRAGMENTATION OLIGOMERS 3M INNOVATIVE PROPERTIES COMPANY (US) 2015-11-19 US disclosed
US-20150284601-A1 LIQUID OPTICAL ADHESIVE COMPOSITIONS 3M INNOVATIVE PROPERTIES COMPANY 2015-10-08 US disclosed
US-20150203658-A1 ADDITION-FRAGMENTATION AGENTS SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2015-07-23 US disclosed
US-20150184031-A1 LIQUID OPTICAL ADHESIVE COMPOSITIONS 3M INNOVATIVE PROPERTIES COMPANY 2015-07-02 US disclosed
US-8980969-B2 Addition-fragmentation agents 3M INNOVATIVE PROPERTIES COMPANY (US) 2015-03-17 US disclosed
US-7659323-B2 crosslinked hydrophilic gel absorbent layer of a crosslinkable oligomer formualation containing polyoxyethylene or ethyelne oxide-propylene oxide copolymer end capped with hydroxymethyl methacryalate; a copolymer such as hydroxyethyl methacrylate, dimethyl acryalmide, vinypyrrolidone; wound dressings 3M INNOVATIVE PROPERTIES COMPANY (US) 2010-02-09 US disclosed
US-20070191506-A1 CURABLE COMPOSITIONS FOR OPTICAL ARTICLES 3M INNOVATIVE PROPERTIES COMPANY 2007-08-16 US disclosed
US-7074839-B2 Crosslinkable hydrophilic materials from reactive oligomers having pendent photoinitiator groups 3M INNOVATIVE PROPERTIES COMPANY (US) 2006-07-11 US disclosed
US-20050192370-A1 Crosslinkable hydrophilic materials from reactive oligomers having pendent photoinitiator groups 3M INNOVATIVE PROPERTIES COMPANY 2005-09-01 US disclosed
US-6664306-B2 Melt processable composition comprising dendritic polymer having plurality of pendent free-radically polymerizable functional groups and polymeric photoinitiator 3M INNOVATIVE PROPERTIES COMPANY 2003-12-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150328086-A1 ADDITION-FRAGMENTATION OLIGOMERS FGB, ZYX, APBA1 ALDH1A1 1881/4885RARB 2340/4885TP53 1948/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.