SCHEMBL10620646

SCHEMBL10620646

C=C(CCc1ccc(N)cc1)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GFER P55789 1/20 0.48
MAOB P27338 4/20 0.47
MAOA P21397 2/20 0.47
FFAR1 O14842 4/20 0.42
KEAP1 Q14145 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
RECQL P46063 1/20 0.40
ALDH1A1 P00352 2/20 0.38
CYP3A4 P08684 1/20 0.38
TSHR P16473 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
HDAC1 Q13547 1/20 0.38
ITGB1 P05556 1/20 0.37
ITGA5 P08648 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29527824 0.85 GFER (0.48) GFERMAOBMAOAFFAR1CA1
SCHEMBL1137129 0.82 ESR1 (0.50) FFAR1CA2RECQLALDH1A1CYP3A4
SCHEMBL7634724 0.82 FFAR1 (0.44) FFAR1KEAP1CA1CA2ALDH1A1
SCHEMBL17940817 0.82 FFAR1 (0.64) FFAR1KEAP1ALDH1A1TDP1HDAC1
SCHEMBL30529 0.82 KEAP1 (0.61) MAOBMAOAFFAR1KEAP1NPC1
SCHEMBL1921016 0.81 FFAR1 (0.54) FFAR1ALDH1A1TDP1
SCHEMBL1920376 0.81 FFAR1 (0.50) FFAR1HDAC1
SCHEMBL3682243 0.81 ALDH1A1 (0.48) FFAR1KEAP1RECQLALDH1A1TSHR
SCHEMBL1921168 0.81 L3MBTL1 (0.51) FFAR1KEAP1ALDH1A1
SCHEMBL1920945 0.81 FFAR1 (0.50) FFAR1HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0179155-B1 SOLAR CELL ARRAY PANEL AND METHOD OF MANUFACTURE Hughes Aircraft Company (US) 1988-06-08 EP disclosed
EP-0179155-A1 SOLAR CELL ARRAY PANEL AND METHOD OF MANUFACTURE. HUGHES AIRCRAFT CO (US) 1986-04-30 EP disclosed
EP-0071372-B1 ISOIMIDE CONTAINING OLIGOMERS Hughes Aircraft Company (US) 1986-01-22 EP disclosed
WO-1985005222-A1 SOLAR CELL ARRAY PANEL AND METHOD OF MANUFACTURE HUGHES AIRCRAFT COMPANY (US) 1985-11-21 WO disclosed
US-4542257-A CONNECTING SOLAR CELLS BONDED TO FIBER REINFORCED POLYIMIDE HUGHES AIRCRAFT COMPANY (US) 1985-09-17 US disclosed
US-4496711-A CYCLIZATION AT LOW TEMPERATURES THE REACTION PRODUCT ON AN ANHYDRIDE, DIAMINE AND AMINE-CONTAINING ACETYLENE OR NITRILE HUGHES AIRCRAFT COMPANY (US) 1985-01-29 US disclosed
US-4495342-A Isoimide containing oligomers HUGHES AIRCRAFT COMPANY (US) 1985-01-22 US disclosed
US-4485231-A ADDITION POLYMERIZABLE HUGHES AIRCRAFT COMPANY (US) 1984-11-27 US disclosed
US-4438273-A Isoimide containing oligomers HUGHES AIRCRAFT COMPANY (US) 1984-03-20 US disclosed
EP-0071372-A1 Isoimide containing oligomers Hughes Aircraft Company (US) 1983-02-09 EP disclosed