Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | ALB | P02768 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | CFTR | P13569 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1538293 | 0.92 | TSHR (0.65) | KDM4EHSD17B10ALDH1A1TSHRLMNA | |
| SCHEMBL3181067 | 0.88 | SELL (0.56) | KDM4EHSD17B10ALDH1A1TSHRHPGD | |
| SCHEMBL2148841 | 0.84 | LMNA (0.57) | KDM4EHSD17B10ALDH1A1TSHRLMNA | |
| SCHEMBL110532 | 0.82 | ALDH1A1 (0.70) | KDM4EHSD17B10ALDH1A1TSHRHPGD | |
| Methyl 2,3-Dihydroxybenzoate SCHEMBL29467417 | 0.82 | KDM4E (0.56) | KDM4EHSD17B10ALDH1A1TSHRHPGD | |
| SCHEMBL9631230 | 0.82 | MAPT (0.57) | KDM4EHSD17B10ALDH1A1TSHRHPGD | |
| Methyl 2,3-Dihydroxybenzoate SCHEMBL433982 | 0.82 | LMNA (0.70) | KDM4EHSD17B10ALDH1A1TSHRHPGD | |
| SCHEMBL31440979 | 0.81 | ALDH1A1 (0.64) | KDM4EHSD17B10ALDH1A1TSHRHPGD | |
| SCHEMBL40534 | 0.81 | ALDH1A1 (0.64) | KDM4EHSD17B10ALDH1A1TSHRHPGD | |
| Dimethyl Phthalate SCHEMBL9436120 | 0.81 | ALDH1A1 (0.64) | KDM4EHSD17B10ALDH1A1TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104781303-B | Epoxy-resin systems for the tetramine containing polyethylene of resin transfer moulding method | 陶氏环球技术有限责任公司 | 2017-11-10 | — | — | CN | claimed |
| CN-104781303-A | Epoxy resin system containing polyethylene tetraamines for resin transfer molding processes | DOW GLOBAL TECHNOLOGIES LLC | 2015-07-15 | — | — | CN | claimed |
| EP-4573087-A1 | USE OF (ISOINDOLIN-2-YL)(4-HYDROXY-3-(ISOINDOLINE-2-CARBONYL)PHENYL)METHANONES IN THE TREATMENT OF TUMOR NECROSIS FACTOR RECEPTOR-ASSOCIATED PROTEIN 1 DYSFUNCTION | University of Notre Dame du Lac (US) | 2025-06-25 | — | — | EP | disclosed |
| WO-2024044553-A1 | USE OF (ISOINDOLIN-2-YL)(4-HYDROXY-3-(ISOINDOLINE-2-CARBONYL)PHENYL)METHANONES IN THE TREATMENT OF TUMOR NECROSIS FACTOR RECEPTOR-ASSOCIATED PROTEIN 1 DYSFUNCTION | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2024-02-29 | — | — | WO | disclosed |
| US-20180042899-A1 | Method of Treating Transplant Rejection and Autoimmune Diseases | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2018-02-15 | — | — | US | disclosed |
| CN-104781303-B | Epoxy-resin systems for the tetramine containing polyethylene of resin transfer moulding method | 陶氏环球技术有限责任公司 | 2017-11-10 | — | — | CN | disclosed |
| CN-102385248-B | Photosensitive polymer combination | SUMITOMO CHEMICAL CO., LTD. (JP) | 2016-12-14 | — | — | CN | disclosed |
| CN-106133020-A | Modifying epoxy resin by organosilicon and containing the compositions of this epoxy resin and solidfied material thereof | 信越化学工业株式会社 | 2016-11-16 | — | — | CN | disclosed |
| CN-104781303-A | Epoxy resin system containing polyethylene tetraamines for resin transfer molding processes | DOW GLOBAL TECHNOLOGIES LLC | 2015-07-15 | — | — | CN | disclosed |
| US-8703750-B2 | Mixtures and methods for the induction of resistance in plants | ISAGRO S.P.A. (IT) | 2014-04-22 | — | — | US | disclosed |
| US-20140050694-A1 | Method of Treating Transplant Rejection and Autoimmune Diseases | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2014-02-20 | — | — | US | disclosed |
| CN-101125138-A | Inhibitors against the production and release of inflammatory cytokines | INST MED MOLECULAR DESIGN INC (JP) | 2008-02-20 | — | — | CN | disclosed |
| US-20070173459-A1 | Mixtures and methods for the induction of resistance in plants | ISAGRO S.P.A. (IT) | 2007-07-26 | — | — | US | disclosed |
| CN-1925748-A | Mixtures and methods for inducing resistance in plants | ISAGRO SPA (IT) | 2007-03-07 | — | — | CN | disclosed |
| EP-1720408-A1 | MIXTURES AND METHODS FOR THE INDUCTION OF RESISTANCE IN PLANTS | ISAGRO S.p.A. (IT) | 2006-11-15 | — | — | EP | disclosed |
| WO-2005094580-A1 | MIXTURES AND METHODS FOR THE INDUCTION OF RESISTANCE IN PLANTS | ISAGRO S.P.A. (IT) | 2005-10-13 | — | — | WO | disclosed |
| CN-1658856-A | Cancer therapeutic agent | INST MED MOLECULAR DESIGN INC (JP) | 2005-08-24 | — | — | CN | disclosed |
| CN-1658857-A | NF-kB activation inhibitor | INST MED MOLECULAR DESIGN INC (JP) | 2005-08-24 | — | — | CN | disclosed |
| CN-1658858-A | Remedies for neurodegenerative diseases | INST MED MOLECULAR DESIGN INC (JP) | 2005-08-24 | — | — | CN | disclosed |
| CN-1489458-A | Inflammatory cytokine production dissociation inhibitor | ��ʽ����ҽҩ��������о��� | 2004-04-14 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070173459-A1 | Mixtures and methods for the induction of resistance in plants | SLC11A2, MYD88, ME2 | KDM4E 4408/4885HSD17B10 2526/4885ALDH1A1 2944/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.