SCHEMBL1538293

SCHEMBL1538293

COC(=O)c1cccc(C(=O)OC)c1O

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.65
LMNA P02545 1/20 0.65
CA1 P00915 4/20 0.58
CA2 P00918 4/20 0.58
CA9 Q16790 4/20 0.58
CA12 O43570 3/20 0.58
CA7 P43166 3/20 0.58
CA14 Q9ULX7 3/20 0.58
ALDH1A1 P00352 1/20 0.57
CFTR P13569 1/20 0.57
HSD17B10 Q99714 1/20 0.57
KDM4E B2RXH2 2/20 0.55
POLB P06746 1/20 0.55
ATM Q13315 1/20 0.55
CXCR2 P25025 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
MAPT P10636 2/20 0.51
MITF O75030 1/20 0.51
CA5A P35218 1/20 0.50
ALOX15 P16050 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3682394 0.92 KDM4E (0.57) TSHRLMNACA1CA2CA9
SCHEMBL2148841 0.92 LMNA (0.57) TSHRLMNACA1CA2CA9
Methyl 2,3-Dihydroxybenzoate SCHEMBL433982 0.89 LMNA (0.70) TSHRLMNACA1CA2CA9
SCHEMBL13444406 0.88 LMNA (0.53) TSHRLMNACA1CA2CA9
SCHEMBL334485 0.87 ALDH1A1 (0.62) TSHRLMNACA1CA2CA9
SCHEMBL28236597 0.87 LMNA (0.52) TSHRLMNACA1CA2CA9
SCHEMBL15906683 0.87 LMNA (0.52) TSHRLMNACA1CA2CA9
SCHEMBL8875029 0.87 TSHR (0.52) TSHRLMNACA1CA2CA9
SCHEMBL204668 0.86 ALDH1A1 (0.69) TSHRLMNACA1CA2CA9
SCHEMBL9639243 0.86 TSHR (0.55) TSHRLMNACA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107935840-A A kind of 4 Hydroxy M Phthalic Acid derivatives and synthetic method 常州工程职业技术学院 2018-04-20 CN claimed
CN-105949047-A Method for extracting 4-hydroxy-m-phthalic acid from wintergreen oil production waste slag 东南大学 2016-09-21 CN claimed
US-9440891-B2 Palladium-catalyzed decarbonylation of fatty acid anhydrides for the production of linear alpha olefins CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2016-09-13 US claimed
US-4833023-A CONTAINING SOILD PLASTICIZER MITSUBISHI PAPER MILLS, LTD. (JP) 1989-05-23 US claimed
US-4745026-A FINE PARTICLE SOLID PLASTICIZER MITSUBISHI PAPER MILLS, LTD. (JP) 1988-05-17 US claimed
EP-0132717-B1 HEAT-SENSITIVE RECORD MATERIAL KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1987-04-22 EP claimed
US-4540999-A HYDROXYPHTHALATE, CHROMOGEN KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1985-09-10 US claimed
EP-0132717-A1 Heat-sensitive record material KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1985-02-13 EP claimed
US-20260022099-A1 ARYL HYDROCARBON RECEPTOR AGONISTS AND USES THEREOF NEXYS THERAPEUTICS, INC. (US) 2026-01-22 US disclosed
US-12371408-B2 Aryl hydrocarbon receptor agonists and uses thereof NEXYS THERAPEUTICS, INC. (US) 2025-07-29 US disclosed
WO-2025045826-A1 COMPOUNDS FOR ACTIVATION OF FGFR1 SIGNALING THE CULTIVATED B. GMBH (DE) 2025-03-06 WO disclosed
CN-116082181-B Method for preparing 3-amino-5-ethoxy-benzoic acid 爱斯特(成都)生物制药股份有限公司 2025-03-04 CN disclosed
US-12168646-B2 Aryl hydrocarbon receptor agonists and uses thereof NEXYS THERAPEUTICS, INC. (US) 2024-12-17 US disclosed
EP-4472953-A1 ARYL HYDROCARBON RECEPTOR AGONISTS AND USES THEREOF Nexys Therapeutics, Inc. (US) 2024-12-11 EP disclosed
US-5466553-A Phenolic hydroxyl group-containing polyester binder resin TOMOEGAWA PAPER CO., LTD. (JP) 1995-11-14 US disclosed
EP-0617337-A2 Toner for developing electrostatic image TOMOEGAWA PAPER CO. LTD. (JP) 1994-09-28 EP disclosed
US-4833023-A CONTAINING SOILD PLASTICIZER MITSUBISHI PAPER MILLS, LTD. (JP) 1989-05-23 US disclosed
US-4745026-A FINE PARTICLE SOLID PLASTICIZER MITSUBISHI PAPER MILLS, LTD. (JP) 1988-05-17 US disclosed
US-4442176-A CHROMOGEN, HYDROXYPHTHALIC DIESTER OF SPECIFIED MELTING POINT KAWASAKI KASEI CHEMICALS LTD. (JP) 1984-04-10 US disclosed
US-3940543-A BLOCK CO-POLYESTER MITSUBISHI RAYON CO., LTD. (JA) 1976-02-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12371408-B2 Aryl hydrocarbon receptor agonists and uses thereof AHR, ARNT, NR1H2 TSHR 352/4885LMNA 4253/4885CA1 4417/4885
US-20260022099-A1 ARYL HYDROCARBON RECEPTOR AGONISTS AND USES THEREOF AHR, NR1H4, CNR1 TSHR 254/4885LMNA 3897/4885CA1 2945/4885
US-12168646-B2 Aryl hydrocarbon receptor agonists and uses thereof AHR, ARNT, NR1H2 TSHR 352/4885LMNA 4253/4885CA1 4417/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.