Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUAK1 | O60285 | 1/20 | 0.58 |
| ▸ | IGF1R | P08069 | 1/20 | 0.58 |
| ▸ | MET | P08581 | 1/20 | 0.58 |
| ▸ | PIM1 | P11309 | 1/20 | 0.58 |
| ▸ | SRC | P12931 | 1/20 | 0.58 |
| ▸ | AXL | P30530 | 1/20 | 0.58 |
| ▸ | AKT1 | P31749 | 1/20 | 0.58 |
| ▸ | KDR | P35968 | 1/20 | 0.58 |
| ▸ | NEK2 | P51955 | 1/20 | 0.58 |
| ▸ | PLK1 | P53350 | 1/20 | 0.58 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.58 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.58 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.58 |
| ▸ | NEK6 | Q9HC98 | 1/20 | 0.58 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.58 |
| ▸ | MAOA | P21397 | 11/20 | 0.57 |
| ▸ | IMPDH2 | P12268 | 4/20 | 0.51 |
| ▸ | IMPDH1 | P20839 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17280322 | 0.79 | NUAK1 (0.54) | NUAK1IGF1RMETPIM1SRC | |
| SCHEMBL16870479 | 0.74 | KDM4E (0.47) | NUAK1IGF1RMETPIM1SRC | |
| SCHEMBL12149642 | 0.73 | NUAK1 (0.72) | NUAK1IGF1RMETPIM1SRC | |
| SCHEMBL31733872 | 0.73 | MAOA (1.00) | MAOAMAOB | |
| SCHEMBL30487600 | 0.73 | MAOA (1.00) | MAOAMAOB | |
| SCHEMBL3417433 | 0.72 | MAOA (0.49) | NUAK1IGF1RMETPIM1SRC | |
| 5,7-Dihydroxy-4-Methylphthalide SCHEMBL3505368 | 0.70 | NUAK1 (0.58) | NUAK1IGF1RMETPIM1SRC | |
| SCHEMBL16870295 | 0.70 | MAOA (0.68) | MAOAMAOB | |
| SCHEMBL9579461 | 0.69 | MAOA (0.47) | MAOAIMPDH2KDM4EGAAMEN1 | |
| SCHEMBL27881769 | 0.69 | NUAK1 (0.72) | NUAK1IGF1RMETPIM1SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100203175-A1 | DEGLYCATION OF AGEs | BASF BEAUTY CARE SOLUTIONS FRANCE S.A.S. (FR) | 2010-08-12 | — | — | US | claimed |
| CN-101765432-A | AGE deglycation | BASF BEAUTY CARE SOLUTIONS F | 2010-06-30 | — | — | CN | claimed |
| EP-3342396-B1 | EXTERNAL PREPARATION FOR SKIN FOR REDUCING SKIN YELLOWNESS | HAYASHIBARA CO (JP) | 2023-04-12 | — | — | EP | disclosed |
| EP-3398585-B1 | EXTERNAL DERMAL COMPOSITION FOR ANTI-AGEING AND METHOD FOR PRODUCING THE SAME | HAYASHIBARA CO (JP) | 2020-02-26 | — | — | EP | disclosed |
| US-10568827-B2 | External dermal agent for reducing yellowish dullness | Hayashibara Co., Ltd. (JP) | 2020-02-25 | — | — | US | disclosed |
| US-20190008747-A1 | EXTERNAL DERMAL COMPOSITION FOR ANTI-AGEING AND METHOD FOR PRODUCING THE SAME | Hayashibara Co., Ltd. (JP) | 2019-01-10 | — | — | US | disclosed |
| EP-3398585-A1 | EXTERNAL DERMAL COMPOSITION FOR ANTI-AGEING AND METHOD FOR PRODUCING THE SAME | Hayashibara Co., Ltd. (JP) | 2018-11-07 | — | — | EP | disclosed |
| US-10111822-B2 | External dermal composition for anti-ageing and method for producing the same | Hayashibara Co., Ltd. (JP) | 2018-10-30 | — | — | US | disclosed |
| US-20180243195-A1 | External dermal agent for reducing yellowish dullness | NAGASE VIITA CO., LTD. (JP) | 2018-08-30 | — | — | US | disclosed |
| EP-2939657-B1 | SKIN-EXTERIOR ANTI-AGEING COMPOSITION AND PRODUCTION METHOD THEREFOR | HAYASHIBARA CO (JP) | 2018-08-08 | — | — | EP | disclosed |
| EP-3342396-A1 | EXTERNAL PREPARATION FOR SKIN FOR REDUCING SKIN YELLOWNESS | Hayashibara Co., Ltd. (JP) | 2018-07-04 | — | — | EP | disclosed |
| CN-107920981-A | Skin external preparation for reducing dark yellow | 株式会社林原 | 2018-04-17 | — | — | CN | disclosed |
| US-20150342854-A1 | EXTERNAL DERMAL COMPOSITION FOR ANTI-AGEING AND METHOD FOR PRODUCING THE SAME | Hayashibara Co., Ltd. (JP) | 2015-12-03 | — | — | US | disclosed |
| EP-2939657-A1 | SKIN-EXTERIOR ANTI-AGEING COMPOSITION AND PRODUCTION METHOD THEREFOR | Hayashibara Co., Ltd. (JP) | 2015-11-04 | — | — | EP | disclosed |
| CN-103816095-A | Deglycation of AGEs | BASE BEAUTY CARE SOLUTIONS FRANCE S A S | 2014-05-28 | — | — | CN | disclosed |
| US-20100203175-A1 | DEGLYCATION OF AGEs | BASF BEAUTY CARE SOLUTIONS FRANCE S.A.S. (FR) | 2010-08-12 | — | — | US | disclosed |
| CN-101765432-A | AGE deglycation | BASF BEAUTY CARE SOLUTIONS F | 2010-06-30 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180243195-A1 | External dermal agent for reducing yellowish dullness | FUT5, ENGASE, FUT6 | NUAK1 3777/4885IGF1R 2698/4885MET 4189/4885 |
| US-10568827-B2 | External dermal agent for reducing yellowish dullness | FUT5, ENGASE, FUT6 | NUAK1 3777/4885IGF1R 2698/4885MET 4189/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.