Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GSR | P00390 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL366294 | 0.80 | FAAH (0.43) | FAAHKMT2AMAPTNPSR1KDM4E | |
| SCHEMBL27332943 | 0.73 | PTGS2 (0.47) | FAAHPTGS2PTGS1LMNACYP2C9 | |
| SCHEMBL5526317 | 0.70 | GSR (0.42) | KMT2AMAPTNPSR1KDM4ETDP1 | |
| SCHEMBL508956 | 0.69 | PTGS2 (0.50) | FAAHKMT2AMAPTMEN1PTGS2 | |
| SCHEMBL5431716 | 0.69 | TSHR (0.52) | KMT2AMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL13074658 | 0.69 | TSHR (0.52) | KMT2AMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL3410010 | 0.68 | ALDH1A1 (0.50) | FAAHKMT2AALDH1A1MEN1PTGS2 | |
| SCHEMBL13389325 | 0.68 | ALDH1A1 (0.50) | FAAHKMT2AALDH1A1MEN1PTGS2 | |
| SCHEMBL10728103 | 0.68 | PTGS2 (0.48) | FAAHPTGS2CYP2D6 | |
| SCHEMBL4588469 | 0.67 | PTGS2 (0.47) | FAAHKMT2AMEN1PTGS2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012009372-A2 | TRIAZOLIUM CARBENE CATALYSTS AND PROCESSES FOR ASYMMETRIC CARBON-CARBON BOND FORMATION | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2012-01-19 | — | — | WO | claimed |